Priyanka Gorijala
Overview
Explore the profile of Priyanka Gorijala including associated specialties, affiliations and a list of published articles.
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22
Citations
76
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Recent Articles
1.
Patel M, Pottier C, Fan K, Cetin A, Johnson M, Ali M, et al.
Hum Mol Genet
. 2025 Feb;
PMID: 39927718
Amyloid-PET imaging tracks the accumulation of amyloid beta (Aβ) deposits in the brain. Amyloid plaques accumulation may begin 10 to 20 years before the individual experiences clinical symptoms associated with...
2.
Wang C, Yang C, Western D, Ali M, Wang Y, Phuah C, et al.
Nat Genet
. 2024 Nov;
56(12):2685-2695.
PMID: 39528826
Brain metabolism perturbation can contribute to traits and diseases. We conducted a genome-wide association study for cerebrospinal fluid (CSF) and brain metabolite levels, identifying 205 independent associations (47.3% new signals,...
3.
Western D, Timsina J, Wang L, Wang C, Yang C, Phillips B, et al.
Nat Genet
. 2024 Nov;
56(12):2672-2684.
PMID: 39528825
The integration of quantitative trait loci (QTLs) with disease genome-wide association studies (GWASs) has proven successful in prioritizing candidate genes at disease-associated loci. QTL mapping has been focused on multi-tissue...
4.
Anastasi F, Genius P, Rodriguez-Fernandez B, Yang C, Gorijala P, Timsina J, et al.
Res Sq
. 2024 Nov;
PMID: 39483923
Background: While numerous studies have identified blood proteins that modulate brain aging in mice, the direct translation of these findings to human health remains a substantial challenge. Bridging this gap...
5.
Shen Y, Timsina J, Heo G, Beric A, Ali M, Wang C, et al.
Cell
. 2024 Sep;
187(22):6309-6326.e15.
PMID: 39332414
In this high-throughput proteomic study of autosomal dominant Alzheimer's disease (ADAD), we sought to identify early biomarkers in cerebrospinal fluid (CSF) for disease monitoring and treatment strategies. We examined CSF...
6.
Anastasi F, Genius P, Rodriguez-Fernandez B, Yang C, Gorijala P, Timsina J, et al.
medRxiv
. 2024 Aug;
PMID: 39211866
Several studies have identified blood proteins that influence brain aging performance in mice, yet translating these findings to humans remains challenging. Here we found that higher predicted plasma levels of...
7.
Cruchaga C, Yang C, Gorijala P, Timsina J, Wang L, Liu M, et al.
Res Sq
. 2024 Aug;
PMID: 39108494
Initially focused on the European population, multiple genome-wide association studies (GWAS) of complex diseases, such as type-2 diabetes (T2D), have now extended to other populations. However, to date, few ancestry-matched...
8.
Marsh T, Western D, Timsina J, Gorijala P, Yang C, Pastor P, et al.
Alzheimers Dement
. 2024 Jul;
20(9):6423-6440.
PMID: 39077866
Introduction: Plasma has been proposed as an alternative to cerebrospinal fluid (CSF) for measuring Alzheimer's disease (AD) biomarkers, but no studies have analyzed in detail which biofluid is more informative...
9.
Fernandez M, Liu M, Beric A, Johnson M, Cetin A, Patel M, et al.
Sci Data
. 2024 Jul;
11(1):768.
PMID: 38997326
The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington University in St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical, social, pathological, and molecular understanding of...
10.
Cruchaga C, Bradley J, Western D, Wang C, Lucio Da Fonseca E, Neupane A, et al.
Res Sq
. 2024 Jun;
PMID: 38883718
Alzheimer Disease (AD) is a highly polygenic disease that presents with relatively earlier onset (≤70yo; EOAD) in about 5% of cases. Around 90% of these EOAD cases remain unexplained by...