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Primo N Lara Jr

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Articles 205
Citations 6380
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Recent Articles
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Swami U, Jo Y, Narang A, Plets M, Hage Chehade C, Gebrael G, et al.
Eur Urol Oncol . 2024 Nov; PMID: 39521639
Although obesity has been associated with better overall survival (OS) among patients with metastatic castration-resistant prostate cancer, its association with OS has not been extensively explored in metastatic hormone-sensitive prostate...
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Ryan C, Tangen C, Lara Jr P
Lancet . 2024 Nov; 404(10465):1810. PMID: 39521508
No abstract available.
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Goldkorn A, Tangen C, Plets M, Bsteh D, Xu T, Pinski J, et al.
JAMA Netw Open . 2024 Oct; 7(10):e2437871. PMID: 39374015
Importance: In metastatic hormone-sensitive prostate cancer (mHSPC), new first-line combination therapies have enhanced overall survival (OS), but clinical outcomes for individual patients vary greatly and are difficult to predict. Peripheral...
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Barata P, Tangen C, Plets M, Thompson Jr I, Narayan V, George D, et al.
J Clin Oncol . 2024 Sep; 42(33):3911-3916. PMID: 39255440
JCO Mesenchymal-epithelial transition (MET) signaling pathway plays a role in the pathogenesis of selected patients with papillary renal cell carcinoma (PRCC). In the phase II PAPMET trial (ClinicalTrials.gov identifier: NCT02761057),...
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Gulati S, Tangen C, Ryan C, Vaishampayan U, Shuch B, Barata P, et al.
JAMA Netw Open . 2024 Aug; 7(8):e2425288. PMID: 39106067
Importance: Clinical trial data on adjuvant therapy in patients with non-clear cell renal cell carcinoma (RCC) are scant. Objective: To evaluate the effect of adjuvant everolimus after nephrectomy on recurrence-free...
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Lara Jr P, Villanueva L, Ibanez C, Erman M, Lee J, Heinrich D, et al.
BMC Cancer . 2024 Jul; 23(Suppl 1):1253. PMID: 39054430
Background: Immunotherapy-based combinations have emerged as standard therapies for patients with metastatic renal cell carcinoma (mRCC). Pembrolizumab, a PD-1 inhibitor, combined with epacadostat, an indoleamine 2,3-deoxygenase 1 selective inhibitor, demonstrated...
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Tripathi A, Tangen C, Plets M, Li X, Tretiakova M, Humphrey P, et al.
BJU Int . 2024 Jul; 134(4):596-601. PMID: 39014969
Objective: To evaluate the clinical significance of subtyping (type 1 vs 2) of papillary renal cell carcinoma (PRCC) in patients treated with targeted therapy, as well as the concordance, sensitivity...
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Gebrael G, Jo Y, Swami U, Plets M, Hage Chehade C, Narang A, et al.
JAMA Netw Open . 2024 Jul; 7(7):e2419966. PMID: 38980676
Importance: The presence of bone pain is significantly associated with worse overall survival (OS) in patients with castration-resistant prostate cancer. However, there are few data regarding bone pain and survival...
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Lara Jr P, Tangen C, Heath E, Gulati S, Stein M, Meng M, et al.
Eur Urol . 2024 May; 86(3):258-264. PMID: 38811313
Background And Objective: EVEREST is a phase 3 trial in patients with renal cell cancer (RCC) at intermediate-high or very high risk of recurrence after nephrectomy who were randomized to...