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Prem Subramaniam

Explore the profile of Prem Subramaniam including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 229
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Recent Articles
1.
Hu L, Douglass E, Turunen M, Pampou S, Grunn A, Realubit R, et al.
bioRxiv . 2023 Oct; PMID: 37873470
The Mechanism of Action (MoA) of a drug is generally represented as a small, non-tissue-specific repertoire of high-affinity binding targets. Yet, drug activity and polypharmacology are increasingly associated with a...
2.
Arumugam K, Shin W, Schiavone V, Vlahos L, Tu X, Carnevali D, et al.
Cell Rep . 2020 Dec; 33(10):108474. PMID: 33296649
Bi-species, fusion-mediated, somatic cell reprogramming allows precise, organism-specific tracking of unknown lineage drivers. The fusion of Tcf7l1 murine embryonic stem cells with EBV-transformed human B cell lymphocytes, leads to the...
3.
Woo J, Shimoni Y, Yang W, Subramaniam P, Iyer A, Nicoletti P, et al.
Cell . 2015 Jul; 162(2):441-451. PMID: 26186195
Genome-wide identification of the mechanism of action (MoA) of small-molecule compounds characterizing their targets, effectors, and activity modulators represents a highly relevant yet elusive goal, with critical implications for assessment...
4.
Minond D, Saldanha S, Subramaniam P, Spaargaren M, Spicer T, Fotsing J, et al.
Bioorg Med Chem . 2009 Jun; 17(14):5027-37. PMID: 19553129
VIM-2 is an Ambler class B metallo-beta-lactamase (MBL) capable of hydrolyzing a broad-spectrum of beta-lactam antibiotics. Although the discovery and development of MBL inhibitors continue to be an area of...
5.
Grover R, Pond S, Cui Q, Subramaniam P, Case D, Millar D, et al.
Angew Chem Int Ed Engl . 2007 Feb; 46(16):2839-43. PMID: 17295375
No abstract available.
6.
Guzeloglu A, Subramaniam P, Michel F, Thatcher W
Biol Reprod . 2004 Feb; 71(1):170-6. PMID: 14985247
A series of experiments were undertaken to examine the effects of interferon (IFN)-tau on regulation of prostaglandin H synthase (PGHS)-2 mRNA in bovine endometrial (BEND) cells as a means to...