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Preeti Bharaj

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Articles 29
Citations 1002
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Recent Articles
1.
Ma M, Jiang Q, Chen C, Badeti S, Wang X, Zeng C, et al.
J Virol . 2024 May; 98(6):e0003824. PMID: 38767356
Importance: Chimeric antigen receptor (CAR)-NK cells can be "off-the-shelf" products that treat various diseases, including cancer, infections, and autoimmune diseases. In this study, we engineered natural killer (NK) cells to...
2.
Martinez-Martinez Y, Huante M, Chauhan S, Naqvi K, Bharaj P, Endsley J
NPJ Vaccines . 2023 Oct; 8(1):165. PMID: 37898618
Therapeutic vaccines have promise as adjunctive treatment for tuberculosis (TB) or as preventives against TB relapse. An important development challenge is the limited understanding of T helper (Th) cell roles...
3.
van Tol S, Kalveram B, Ilinykh P, Ronk A, Huang K, Aguilera-Aguirre L, et al.
PLoS Pathog . 2022 May; 18(5):e1010532. PMID: 35533195
Ebola virus (EBOV) VP35 is a polyfunctional protein involved in viral genome packaging, viral polymerase function, and host immune antagonism. The mechanisms regulating VP35's engagement in different functions are not...
4.
Ilinykh P, Periasamy S, Huang K, Kuzmina N, Ramanathan P, Meyer M, et al.
NPJ Vaccines . 2022 Apr; 7(1):47. PMID: 35468973
Respiratory tract vaccination has an advantage of needle-free delivery and induction of mucosal immune response in the portal of SARS-CoV-2 entry. We utilized human parainfluenza virus type 3 vector to...
5.
Hage A, Bharaj P, van Tol S, Giraldo M, Gonzalez-Orozco M, Valerdi K, et al.
Cell Rep . 2022 Mar; 38(10):110434. PMID: 35263596
Type I interferons (IFN-I) are essential to establish antiviral innate immunity. Unanchored (or free) polyubiquitin (poly-Ub) has been shown to regulate IFN-I responses. However, few unanchored poly-Ub interactors are known....
6.
Khakhum N, Bharaj P, Walker D, Torres A, Endsley J
NPJ Vaccines . 2021 May; 6(1):72. PMID: 33986290
Melioidosis, caused by Burkholderia pseudomallei (Bpm), lacks a vaccine. We identify the immune correlates of protection induced by B. mallei ΔtonB Δhcp1 (CLH001) and Bpm ΔtonB Δhcp1 (PBK001) vaccines against...
7.
Letizia A, Ge Y, Vangeti S, Goforth C, Weir D, Kuzmina N, et al.
Lancet Respir Med . 2021 Apr; 9(7):712-720. PMID: 33865504
Background: Whether young adults who are infected with SARS-CoV-2 are at risk of subsequent infection is uncertain. We investigated the risk of subsequent SARS-CoV-2 infection among young adults seropositive for...
8.
van Tol S, Atkins C, Bharaj P, Johnson K, Hage A, Freiberg A, et al.
J Virol . 2019 Nov; 94(2). PMID: 31694946
Several members of the tripartite motif (TRIM) family of E3 ubiquitin ligases regulate immune pathways, including the antiviral type I interferon (IFN-I) system. Previously, we demonstrated that TRIM6 is involved...
9.
Khakhum N, Bharaj P, Myers J, Tapia D, Walker D, Endsley J, et al.
PLoS Negl Trop Dis . 2019 Jul; 13(7):e0007578. PMID: 31306423
Background: Glanders caused by Burkholderia mallei is a re-emerging zoonotic disease affecting solipeds and humans. Furthermore, B. mallei is genetically related to B. pseudomallei, which is the causative agent of...
10.
Khakhum N, Bharaj P, Myers J, Tapia D, Kilgore P, Ross B, et al.
mSphere . 2019 Jan; 4(1). PMID: 30602524
is a Gram-negative facultative intracellular bacterium and the causative agent of melioidosis, a severe infectious disease found throughout the tropics. This organism is closely related to , the etiological agent...