Pratima Nangia-Makker
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Explore the profile of Pratima Nangia-Makker including associated specialties, affiliations and a list of published articles.
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51
Citations
1784
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Recent Articles
1.
Lin Q, Gajan A, Nguyen I, Sharma S, Nangia-Makker P, Firestine S, et al.
Pharm Res
. 2025 Feb;
PMID: 40021546
Purpose: Given its role in cancer development and progression, Rad6 is an underexplored therapeutic target. Previous research identified compound SMI#9 as a small molecule inhibitor of Rad6. Despite its potency,...
2.
Nangia-Makker P, Hogan V, Balan V, Raz A
J Biol Chem
. 2022 Oct;
298(12):102622.
PMID: 36272642
Fibrosis, stiffening and scarring of an organ/tissue due to genetic abnormalities, environmental factors, infection, and/or injury, is responsible for > 40% of all deaths in the industrialized world, and to...
3.
Nangia-Makker P, Shekhar M, Hogan V, Balan V, Raz A
Oncotarget
. 2022 Mar;
13:534-550.
PMID: 35309869
The accepted notion of dNTP transport following cytoplasmic biosynthesis is 'facilitated diffusion'; however, whether this alone is sufficient for moving dNTPs for DNA synthesis remains an open question. The data...
4.
Sarma A, Gajan A, Kim S, Gurdziel K, Mao G, Nangia-Makker P, et al.
Am J Pathol
. 2020 Nov;
191(2):368-384.
PMID: 33181138
Canonical Wnt signaling is critical for melanocyte lineage commitment and melanoma development. RAD6B, a ubiquitin-conjugating enzyme critical for translesion DNA synthesis, potentiates β-catenin stability/activity by inducing proteasome-insensitive polyubiquitination. RAD6B expression...
5.
Farhana L, Sarkar S, Nangia-Makker P, Yu Y, Khosla P, Levi E, et al.
PLoS One
. 2020 Mar;
15(3):e0229823.
PMID: 32196510
The current study was undertaken to investigate the effect of differentially formulated polyphenolic compound Essential Turmeric Oil-Curcumin (ETO-Cur), and Tocotrienol-rich fraction (TRF) of vitamin E isomers on colorectal cancer (CRC)...
6.
Genovese S, Epifano F, Preziuso F, Slater J, Nangia-Makker P, Majumdar A, et al.
Biochem Biophys Res Commun
. 2019 Nov;
522(1):95-99.
PMID: 31740005
Advanced colon cancer is extremely difficult to cure, underscoring the need to develop novel therapeutic agents. Prenylated curcumins that are semisynthetic curcumin derivatives with significant anti-cancer potential have been studied...
7.
Haynes B, Gajan A, Nangia-Makker P, Shekhar M
Biochim Biophys Acta Mol Basis Dis
. 2019 Oct;
1866(1):165561.
PMID: 31639439
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype with few therapy options besides chemotherapy. Although platinum-based drugs have shown initial activity in BRCA1-mutated TNBCs, chemoresistance remains a...
8.
Farhana L, Antaki F, Murshed F, Mahmud H, Judd S, Nangia-Makker P, et al.
World J Gastrointest Pathophysiol
. 2018 Oct;
9(2):47-58.
PMID: 30283710
Aim: To determine whether and to what extent the gut microbiome is involved in regulating racial disparity in colorectal cancer (CRC). Methods: All patients were recruited and experiments were performed...
9.
Saadat N, Liu F, Haynes B, Nangia-Makker P, Bao X, Li J, et al.
Mol Cancer Ther
. 2018 Sep;
17(12):2586-2597.
PMID: 30242094
The triple-negative breast cancer (TNBC) subtype, regardless of their BRCA1 status, has the poorest outcome compared with other breast cancer subtypes, and currently there are no approved targeted therapies for...
10.
Nangia-Makker P, Hogan V, Raz A
Glycobiology
. 2018 Jan;
28(4):172-181.
PMID: 29315388
Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been unique due to the regulatory roles it performs in processes associated with tumor...