Prashant Kaushal
Overview
Explore the profile of Prashant Kaushal including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
47
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0
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Recent Articles
1.
Alvarez P, Tang A, Winters D, Kaushal P, Medina A, Kaczor-Urbanowicz K, et al.
bioRxiv
. 2025 Feb;
PMID: 39896450
Several alphaviruses bypass the blood-brain barrier (BBB), causing debilitating or fatal encephalitis. Sindbis virus (SINV) has been extensively studied to understand alphavirus neuropathogenesis; yet the molecular details of neuroinvasion at...
2.
Kaushal P, Ummadi M, Jang G, Delgado Y, Makanani S, Alba K, et al.
STAR Protoc
. 2024 Nov;
5(4):103286.
PMID: 39488835
Proteins congregate into complexes to perform diverse cellular functions. Protein complexes are remodeled by protein-coding mutations or cellular signaling changes, driving phenotypic outcomes in health and disease. We present an...
3.
Yao Z, Ramachandran S, Huang S, Kim E, Jami-Alahmadi Y, Kaushal P, et al.
EMBO J
. 2024 Sep;
43(20):4625-4655.
PMID: 39261662
Despite their role as innate sentinels, macrophages can serve as cellular reservoirs of chikungunya virus (CHIKV), a highly-pathogenic arthropod-borne alphavirus that has caused large outbreaks among human populations. Here, with...
4.
An Y, Jung Y, Lee K, Kaushal P, Ko I, Shin S, et al.
PLoS One
. 2024 Sep;
19(9):e0307499.
PMID: 39236042
Fibroblast growth factor 2 (FGF2) is an attractive biomaterial for pharmaceuticals and functional cosmetics. To improve the thermo-stability of FGF2, we designed two mutants harboring four-point mutations: FGF2-M1 (D28E/C78L/C96I/S137P) and...
5.
Ryu J, Yan Z, Montano M, Sozmen E, Dixit K, Suryawanshi R, et al.
Nature
. 2024 Aug;
633(8031):905-913.
PMID: 39198643
Life-threatening thrombotic events and neurological symptoms are prevalent in COVID-19 and are persistent in patients with long COVID experiencing post-acute sequelae of SARS-CoV-2 infection. Despite the clinical evidence, the underlying...
6.
Sharma K, Kaushal P, Kumar V
Methods Mol Biol
. 2024 Aug;
2831:133-143.
PMID: 39134848
The molecular mechanisms underlying neurite formation include multiple crosstalk between pathways such as membrane trafficking, intracellular signaling, and actin cytoskeletal rearrangement. To study the proteins involved in such complex pathways,...
7.
Sanchez-Garrido J, Baghshomali Y, Kaushal P, Kozik Z, Perry R, Williams H, et al.
Mucosal Immunol
. 2024 Jun;
17(5):939-957.
PMID: 38936619
Citrobacter rodentium models infection with enteropathogenic Escherichia coli and ulcerative colitis (UC). While C57BL/6 (C57) mice recover, C3H/HeN (C3H) mice succumb to infection, partially due to increased colonic neutrophil elastase...
8.
Kaushal P, Ummadi M, Jang G, Delgado Y, Makanani S, Blanc S, et al.
ArXiv
. 2024 May;
PMID: 38800652
Proteins congregate into complexes to perform fundamental cellular functions. Phenotypic outcomes, in health and disease, are often mechanistically driven by the remodeling of protein complexes by protein-coding mutations or cellular...
9.
Kaushal P, Zhu J, Wan Z, Chen H, Ye J, Luo C
Neuromolecular Med
. 2022 Jul;
25(1):102-119.
PMID: 35779207
Glioblastoma (GBM) is the most malignant and aggressive primary brain tumor and is highly resistant to current therapeutic strategies. Previous studies have demonstrated that reactive oxygen species (ROS) play an...
10.
Lee S, Lee D, Kang M, Kim S, Kwon S, Lee H, et al.
Cell Death Differ
. 2022 May;
29(12):2381-2398.
PMID: 35637285
BRCA1-associated protein-1 (BAP1) is a ubiquitin C-terminal hydrolase domain-containing deubiquitinase with tumor suppressor activity. The gene encoding BAP1 is mutated in various human cancers, with particularly high frequency in kidney...