Prasanna Krishnamurthy
Overview
Explore the profile of Prasanna Krishnamurthy including associated specialties, affiliations and a list of published articles.
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72
Citations
2284
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Recent Articles
11.
Singh S, Henderson J, Patil M, Dubey P, Dubey S, Kannappan R, et al.
Inflamm Res
. 2022 Jan;
71(3):321-330.
PMID: 35020000
Objective And Design: Phagocytosis and clearance of apoptotic cells are essential for inflammation resolution, efficient wound healing, and tissue homeostasis. MicroRNAs are critical modulators of macrophage polarization and function. The...
12.
Zhou J, Singh N, Monnier C, Marszalec W, Gao L, Jin J, et al.
Front Physiol
. 2022 Jan;
12:782767.
PMID: 35002765
BIN1 (amphyphysin-II) is a structural protein involved in T-tubule (TT) formation and phosphatidylinositol-4,5-bisphosphate (PIP2) is responsible for localization of BIN1 to sarcolemma. The goal of this study was to determine...
13.
Patil M, Saheera S, Dubey P, Kahn-Krell A, Govindappa P, Singh S, et al.
Circ Res
. 2021 Oct;
129(11):1006-1020.
PMID: 34623174
[Figure: see text].
14.
Dubey P, Patil M, Singh S, Dubey S, Ahuja P, Verma S, et al.
Mol Cell Biochem
. 2021 Sep;
477(1):129-141.
PMID: 34581943
Endotoxemia triggers life-threatening immune and cardiovascular response that leads to tissue damage, multi-organ failure, and death. The understanding of underlying molecular mechanisms is still evolving. N6-methyladenosine (m6A)-RNA modification plays key...
15.
Sunny S, Challa A, Qiao A, Jyothidasan A, Krishnamurthy P, Ramamurthy M, et al.
Cardiol Cardiovasc Med
. 2021 Sep;
5(5):454-470.
PMID: 34497977
The development of the heart follows a synergic action of several signaling pathways during gestational, pre- & postnatal stages. The current study aimed to investigate whether the myocardium experiences transcriptional...
16.
Henderson J, Dubey P, Patil M, Singh S, Dubey S, Namakkal Soorappan R, et al.
Front Cardiovasc Med
. 2021 Sep;
8:737826.
PMID: 34485421
Doxorubicin (DOX, an anthracycline) is a widely used chemotherapy agent against various forms of cancer; however, it is also known to induce dose-dependent cardiotoxicity leading to adverse complications. Investigating the...
17.
Ranjan P, Kumari R, Goswami S, Li J, Pal H, Suleiman Z, et al.
Front Cardiovasc Med
. 2021 May;
8:676267.
PMID: 33969024
Endothelial cells (ECs) play a critical role in the maintenance of vascular homeostasis and in heart function. It was shown that activated fibroblast-derived exosomes impair cardiomyocyte function in hypertrophic heart,...
18.
Luong H, Singh S, Patil M, Krishnamurthy P
Am J Physiol Heart Circ Physiol
. 2021 Apr;
320(5):H2044-H2057.
PMID: 33834865
Major depressive disorder (MDD) is an independent risk factor for cardiovascular disease (CVD) and its complications; however, causal mechanisms remain unclear. In the present study, we investigate cardiac structural and...
19.
Patil M, Singh S, Henderson J, Krishnamurthy P
J Cell Physiol
. 2020 Oct;
236(5):3366-3382.
PMID: 33078408
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has reached a pandemic level, spreading across the globe by affecting over 33 million people and...
20.
Gao L, Wang L, Wei Y, Krishnamurthy P, Walcott G, Menasche P, et al.
Sci Transl Med
. 2020 Sep;
12(561).
PMID: 32938792
Cell therapy treatment of myocardial infarction (MI) is mediated, in part, by exosomes secreted from transplanted cells. Thus, we compared the efficacy of treatment with a mixture of cardiomyocytes (CMs;...