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Prasad Phapale

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Articles 21
Citations 2195
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Recent Articles
1.
Petrovic D, Slade L, Paikopoulos Y, DAndrea D, Savic N, Stancic A, et al.
Cell Metab . 2025 Feb; 37(3):789. PMID: 39894020
No abstract available.
2.
Spangenberg P, Bessler S, Widera L, Bottek J, Richter M, Thiebes S, et al.
Nat Commun . 2025 Jan; 16(1):1065. PMID: 39870624
Multimodal imaging by matrix-assisted laser desorption ionisation mass spectrometry imaging (MALDI MSI) and microscopy holds potential for understanding pathological mechanisms by mapping molecular signatures from the tissue microenvironment to specific...
3.
Petrovic D, Slade L, Paikopoulos Y, DAndrea D, Savic N, Stancic A, et al.
Cell Metab . 2025 Jan; 37(2):542-556.e14. PMID: 39842434
Ergothioneine (ET), a dietary thione/thiol, is receiving growing attention for its possible benefits in healthy aging and metabolic resilience. Our study investigates ET's effects on healthspan in aged animals, revealing...
4.
Phapale P
Anal Sci Adv . 2024 May; 2(11-12):611-616. PMID: 38715865
Pharmaco-metabolomics uses metabolic phenotypes for the prediction of inter-individual variations in drug response and helps in understanding the mechanisms of drug action. The field has made significant progress over the...
5.
Kanaparthi D, Lampe M, Krohn J, Zhu B, Hildebrand F, Boesen T, et al.
Sci Rep . 2024 Mar; 14(1):7075. PMID: 38528088
Protocells are believed to have existed on early Earth prior to the emergence of prokaryotes. Due to their rudimentary nature, it is widely accepted that these protocells lacked intracellular mechanisms...
6.
Kasarla S, Flocke V, Saw N, Fecke A, Sickmann A, Gunzer M, et al.
J Chromatogr A . 2024 Feb; 1717:464691. PMID: 38301333
Mass spectrometry-based metabolomics with stable isotope labeling (SIL) is an established tool for sensitive and precise analyses of tissue metabolism, its flux, and pathway activities in diverse models of physiology...
7.
Kale D, Fatangare A, Phapale P, Sickmann A
Cells . 2023 Dec; 12(24). PMID: 38132115
The primary prevention, early detection, and treatment of cardiovascular disease (CVD) have been long-standing scientific research goals worldwide. In the past decades, traditional blood lipid profiles have been routinely used...
8.
Mitosch K, Beyss M, Phapale P, Drotleff B, Noh K, Alexandrov T, et al.
PLoS Biol . 2023 Aug; 21(8):e3002198. PMID: 37594988
Pathogenic bacteria proliferating inside mammalian host cells need to rapidly adapt to the intracellular environment. How they achieve this and scavenge essential nutrients from the host has been an open...
9.
Fecke A, Saw N, Kale D, Kasarla S, Sickmann A, Phapale P
Metabolites . 2023 Jul; 13(7). PMID: 37512551
Quantifying metabolites from various biological samples is necessary for the clinical and biomedical translation of metabolomics research. One of the ongoing challenges in biomedical metabolomics studies is the large-scale quantification...
10.
Kale D, Kikul F, Phapale P, Beedgen L, Thiel C, Brugger B
Anal Chem . 2023 Jan; 95(6):3210-3217. PMID: 36716239
Dolichyl monophosphates (DolPs) are essential lipids in glycosylation pathways that are highly conserved across almost all domains of life. The availability of DolP is critical for all glycosylation processes, as...