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Prakash Srinivasan

Explore the profile of Prakash Srinivasan including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 1308
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Recent Articles
1.
Yanik S, Venkatesh V, Gordy J, Alameh M, Meza J, Li Y, et al.
NPJ Vaccines . 2025 Feb; 10(1):34. PMID: 39971939
Malaria resurgence in 2022 saw 249 million clinical cases and 608,000 deaths, mostly in children under five. The WHO-approved circumsporozoite protein (CSP)-targeting vaccines, RTS,S and R21, remain limited in availability....
2.
Anaguano D, Adewale-Fasoro O, Vick G, Yanik S, Blauwkamp J, Fierro M, et al.
PLoS Biol . 2024 Sep; 22(9):e3002801. PMID: 39292724
Malaria is a global and deadly human disease caused by the apicomplexan parasites of the genus Plasmodium. Parasite proliferation within human red blood cells (RBCs) is associated with the clinical...
3.
Yanik S, Yu H, Chaiyawong N, Adewale-Fasoro O, Dinis L, Narayanasamy R, et al.
Am J Trop Med Hyg . 2024 Sep; 111(5):967-976. PMID: 39255803
Rodent malaria models serve as important preclinical antimalarial and vaccine testing tools. Evaluating treatment outcomes in these models often requires manually counting parasite-infected red blood cells (iRBCs), a time-consuming process,...
4.
Yanik S, Venkatesh V, Gordy J, Gabriel-Alameh M, Meza J, Li Y, et al.
Res Sq . 2024 Jul; PMID: 39041038
Resurgence in malaria has been noted in 2022 with 249 million clinical cases resulting in 608,000 deaths, mostly in children under five. Two vaccines, RTS, S, and more recently R21,...
5.
Yanik S, Yu H, Chaiyawong N, Adewale-Fasoro O, Dinis L, Narayanasamy R, et al.
bioRxiv . 2024 Jun; PMID: 38895284
Rodent malaria models serve as important preclinical antimalarial and vaccine testing tools. Evaluating treatment outcomes in these models often requires manually counting parasite-infected red blood cells (iRBCs), a time-consuming process,...
6.
Anaguano D, Adewale-Fasoro O, Vick G, Yanik S, Blauwkamp J, Fierro M, et al.
bioRxiv . 2024 Feb; PMID: 38352500
Malaria is a global and deadly human disease caused by the apicomplexan parasites of the genus . Parasite proliferation within human red blood cells (RBC) is associated with the clinical...
7.
Yanik S, Venkatesh V, Parker M, Ramaswamy R, Diouf A, Sarkar D, et al.
Nat Commun . 2023 Sep; 14(1):5879. PMID: 37735574
Invasion of human erythrocytes by Plasmodium falciparum (Pf) merozoites relies on the interaction between two parasite proteins: apical membrane antigen 1 (AMA1) and rhoptry neck protein 2 (RON2). While antibodies...
8.
Srinivasan P, Yanik S, Venkatesh V, Parker M, Diouf A, Sarkar D, et al.
Res Sq . 2023 May; PMID: 37131813
Invasion of human red blood cells (RBCs) by (Pf) merozoites relies on the interaction between two parasite proteins, apical membrane antigen 1 (AMA1) and rhoptry neck protein 2 (RON2) ....
9.
Zhu D, Dai W, Srinivasan P, McClellan H, Braden D, Allee-Munoz A, et al.
Electrophoresis . 2021 Oct; 43(3):509-515. PMID: 34679212
Rhoptry neck protein 2 (RON2) binds to the hydrophobic groove of apical membrane antigen 1 (AMA1), an interaction essential for invasion of red blood cells (RBCs) by Plasmodium falciparum (Pf)...
10.
Schureck M, Darling J, Merk A, Shao J, Daggupati G, Srinivasan P, et al.
Elife . 2021 Jan; 10. PMID: 33393463
Malaria parasites use the RhopH complex for erythrocyte invasion and channel-mediated nutrient uptake. As the member proteins are unique to Plasmodium spp., how they interact and traffic through subcellular sites...