Pragyanshu Khare
Overview
Explore the profile of Pragyanshu Khare including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
435
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Recent Articles
1.
Khare P, Chand J, Ptakova A, Liguori R, Ferrazzi F, Bishnoi M, et al.
Pharmacol Ther
. 2024 Oct;
263:108727.
PMID: 39384022
The transient receptor potential canonical (TRPC) channels are a group of highly homologous nonselective cation channels from the larger TRP channel family. They have the ability to form homo- and...
2.
Sankina P, Lal R, Khare P, von Horsten S, Fester L, Aggarwal V, et al.
Diabetes Obes Metab
. 2024 Jul;
26(10):4329-4345.
PMID: 39044311
Aim: Brown adipose tissue (BAT) thermogenesis has profound energy-expanding potential, which makes it an attractive target tissue to combat ever-increasing obesity and its other associated metabolic complications. Although it is...
3.
Saxena S, Dagar N, Shelke V, Lech M, Khare P, Gaikwad A
Drug Discov Today
. 2023 Sep;
28(11):103765.
PMID: 37690600
As a high-metabolic-rate organ, the kidney exhibits metabolic reprogramming (MR) in various disease states. Given the >800 million cases of kidney disease worldwide in 2022, understanding the specific bioenergetic pathways...
4.
Bansal Y, Singh R, Sodhi R, Khare P, Dhingra R, Dhingra N, et al.
Neuropharmacology
. 2022 Jun;
215:109169.
PMID: 35753430
Kynurenine pathway, a neuroimmunological pathway plays a substantial role in depression. Consistently, increased levels of neurotoxic metabolite of kynurenine pathway; quinolinic acid (QA) found in the suicidal patients and remitted...
5.
Das N, Vaidya B, Khare P, Bishnoi M, Sharma S
Curr Neurovasc Res
. 2021 Dec;
18(5):497-507.
PMID: 34923943
Background: PPAR gamma co-activator 1α (PGC-1α) is known as the master regulator of mitochondrial biogenesis. It is also a co-activator of peroxisome proliferator-activated receptor-gamma (PPARγ) and plays a role in...
6.
Khare P, Mahajan N, Singh D, Kumar V, Kumar V, Mangal P, et al.
Food Funct
. 2021 Oct;
12(22):11526-11536.
PMID: 34705006
Given the global epidemic of diabesity (co-existence of both diabetes and obesity), novel approaches that target gut hormone secretion and their modulation may offer the dual benefits of increased efficacy...
7.
Mahajan N, Khare P, Kondepudi K, Bishnoi M
Eur J Pharmacol
. 2021 Oct;
912:174553.
PMID: 34627805
Transient receptor potential ankyrin 1 (TRPA1) channel is a calcium permeable, non-selective cation channel, expressed in the sensory neurons and non-neuronal cells of different tissues. Initially studied for its role...
8.
Kaur J, Kumar V, Kumar V, Shafi S, Khare P, Mahajan N, et al.
Int J Obes (Lond)
. 2021 Sep;
46(1):153-161.
PMID: 34564707
Background: Bioactive dietary constituents activating Transient receptor potential (TRP) channels have emerged as promising candidates for the prevention of metabolic disorders. Objective: The present study is an attempt to evaluate...
9.
Kumar V, Khare P, Devi K, Kaur J, Kumar V, Kondepudi K, et al.
Fundam Clin Pharmacol
. 2021 Feb;
35(6):1004-1017.
PMID: 33636045
Short-chain fatty acids (SCFAs), metabolites of colonic bacterial fermentation of complex carbohydrates, are closely related to the release of gut hormones. In this study, we examined the involvement of transient...
10.
Thapak P, Khare P, Bishnoi M, Sharma S
Cell Mol Neurobiol
. 2020 Nov;
42(4):1211-1223.
PMID: 33219878
β-Amyloid (Aβ) peptide is a characteristic feature of Alzheimer's disease (AD) and accumulation of Aβ is associated with loss of synaptic plasticity and neuronal cell death. Aggregation of Aβ initiates...