Pradeep Rajasekhar
Overview
Explore the profile of Pradeep Rajasekhar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
277
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bergamasco M, Ozturk E, Casillas-Espinosa P, Garnham A, Abeysekera W, Wimmer V, et al.
iScience
. 2025 Mar;
28(3):111953.
PMID: 40083716
Loss of the gene encoding the histone acetyltransferase KAT6B (MYST4/MORF/QKF) causes developmental brain abnormalities as well as behavioral and cognitive defects in mice. In humans, heterozygous variants in the gene...
2.
Atkin-Smith G, Santavanond J, Light A, Rimes J, Samson A, Er J, et al.
Nat Commun
. 2024 Oct;
15(1):8802.
PMID: 39438460
Endothelial cells are integral components of all vasculature within complex organisms. As they line the blood vessel wall, endothelial cells are constantly exposed to a variety of molecular factors and...
3.
Sorensen L, Humenick A, Poon S, Han M, Mahdavian N, Rowe M, et al.
J Cell Sci
. 2024 Sep;
137(20).
PMID: 39219476
The enteric nervous system (ENS) consists of an extensive network of neurons and glial cells embedded within the wall of the gastrointestinal (GI) tract. Alterations in neuronal distribution and function...
4.
Chiou S, Al-Ani A, Pan Y, Patel K, Kong I, Whitehead L, et al.
EMBO Mol Med
. 2024 May;
16(7):1717-1749.
PMID: 38750308
Necroptosis is a lytic form of regulated cell death reported to contribute to inflammatory diseases of the gut, skin and lung, as well as ischemic-reperfusion injuries of the kidney, heart...
5.
Rajasekhar P, Carbone S, Johnston S, Nowell C, Wiklendt L, Crampin E, et al.
bioRxiv
. 2024 Jan;
PMID: 38260314
Background: Mechanosensation is an important trigger of physiological processes in the gastrointestinal tract. Aberrant responses to mechanical input are associated with digestive disorders, including visceral hypersensitivity. Transient Receptor Potential Vanilloid...
6.
Kumar K, Wilson J, Nguyen H, McKay L, Wen S, Sepehrizadeh T, et al.
J Am Heart Assoc
. 2024 Jan;
13(3):e033279.
PMID: 38258657
Background: Gut dysmotility is common after ischemic stroke, but the mechanism underlying this response is unknown. Under homeostasis, gut motility is regulated by the neurons of the enteric nervous system...
7.
Joyce R, Pascual R, Heitink L, Capaldo B, Vaillant F, Christie M, et al.
Nat Cell Biol
. 2024 Jan;
26(1):138-152.
PMID: 38216737
Inheritance of a BRCA2 pathogenic variant conveys a substantial life-time risk of breast cancer. Identification of the cell(s)-of-origin of BRCA2-mutant breast cancer and targetable perturbations that contribute to transformation remains...
8.
Retamal J, Grace M, Dill L, Ramirez-Garcia P, Peng S, Gondin A, et al.
Lab Invest
. 2021 Apr;
101(7):851-864.
PMID: 33859334
Endothelial and epithelial cells form physical barriers that modulate the exchange of fluid and molecules. The integrity of these barriers can be influenced by signaling through G protein-coupled receptors (GPCRs)...
9.
Grubisic V, McClain J, Fried D, Grants I, Rajasekhar P, Csizmadia E, et al.
Cell Rep
. 2020 Sep;
32(10):108100.
PMID: 32905782
Mechanisms resulting in abdominal pain include altered neuro-immune interactions in the gastrointestinal tract, but the signaling processes that link immune activation with visceral hypersensitivity are unresolved. We hypothesized that enteric...
10.
Jimenez-Vargas N, Gong J, Wisdom M, Jensen D, Latorre R, Hegron A, et al.
Proc Natl Acad Sci U S A
. 2020 Jun;
117(26):15281-15292.
PMID: 32546520
Whether G protein-coupled receptors signal from endosomes to control important pathophysiological processes and are therapeutic targets is uncertain. We report that opioids from the inflamed colon activate δ-opioid receptors (DOPr)...