Prabir K Chakraborty
Overview
Explore the profile of Prabir K Chakraborty including associated specialties, affiliations and a list of published articles.
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13
Citations
495
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Recent Articles
1.
Chakraborty P, Mustafi S, Xiong X, Dwivedi S, Nesin V, Saha S, et al.
Nat Commun
. 2017 May;
8:14634.
PMID: 28530221
Cancer cells actively promote aerobic glycolysis to sustain their metabolic requirements through mechanisms not always clear. Here, we demonstrate that the gatekeeper of mitochondrial Ca uptake, Mitochondrial Calcium Uptake 1...
2.
Saha S, Xiong X, Chakraborty P, Shameer K, Arvizo R, Kudgus R, et al.
ACS Nano
. 2016 Oct;
10(12):10636-10651.
PMID: 27758098
Altered tumor microenvironment (TME) arising from a bidirectional crosstalk between the pancreatic cancer cells (PCCs) and the pancreatic stellate cells (PSCs) is implicated in the dismal prognosis in pancreatic ductal...
3.
Chakraborty P, Xiong X, Mustafi S, Saha S, Dhanasekaran D, Mandal N, et al.
Oncotarget
. 2015 Oct;
6(35):37367-84.
PMID: 26452259
Elevated lipid metabolism is implicated in poor survival in ovarian cancer (OC) and other cancers; however, current lipogenesis-targeting strategies lack cancer cell specificity. Here, we identify a novel role of...
4.
Saha S, Chakraborty P, Xiong X, Dwivedi S, Mustafi S, Leigh N, et al.
FASEB J
. 2015 Sep;
30(1):441-56.
PMID: 26405298
Deficiencies of the human cystathionine β-synthase (CBS) enzyme are characterized by a plethora of vascular disorders and hyperhomocysteinemia. However, several clinical trials demonstrated that despite reduction in homocysteine levels, disease...
5.
Giri K, Shameer K, Zimmermann M, Saha S, Chakraborty P, Sharma A, et al.
Bioconjug Chem
. 2014 May;
25(6):1078-90.
PMID: 24831101
Molecular identification of protein molecules surrounding nanoparticles (NPs) may provide useful information that influences NP clearance, biodistribution, and toxicity. Hence, nanoproteomics provides specific information about the environment that NPs interact...
6.
Lee W, Chakraborty P, Thevenod F
Int J Cancer
. 2013 Jan;
133(3):556-67.
PMID: 23354914
The multidrug resistance (MDR) P-glycoprotein ABCB1 plays a major role in MDR of malignant cells and is regulated by various transcription factors, including Wnt/β-catenin/TCF4. The transcription factor PITX2 (Pituitary homeobox-2)...
7.
Lee W, Chakraborty P, Roussa E, Wolff N, Thevenod F
Biochim Biophys Acta
. 2012 Jun;
1823(10):1864-76.
PMID: 22705154
Upon endoplasmic reticulum (ER) stress induction, cells endeavor to survive by engaging the adaptive stress response known as the unfolded protein response or by removing aggregated proteins via autophagy. Chronic...
8.
Chakraborty P, Scharner B, Jurasovic J, Messner B, Bernhard D, Thevenod F
Toxicol Lett
. 2010 May;
198(1):69-76.
PMID: 20478370
The transition metal cadmium (Cd) is an environmental pollutant which damages the kidneys. Chronic Cd exposure may induce renal fibrosis and/or cancer, but the signaling pathways involved are not understood....
9.
Chakraborty P, Lee W, Molitor M, Wolff N, Thevenod F
Mol Cancer
. 2010 May;
9:102.
PMID: 20459685
Background: The class 1 carcinogen cadmium (Cd2+) disrupts the E-cadherin/beta-catenin complex of epithelial adherens junctions (AJs) and causes renal cancer. Deregulation of E-cadherin adhesion and changes in Wnt/beta-catenin signaling are...
10.
Mustafi S, Chakraborty P, Raha S
PLoS One
. 2010 Jan;
5(1):e8719.
PMID: 20090934
Background: Resveratrol is known to downregulate the high endogenous level of Heat shock protein 70 (Hsp70) in Chronic Myelogenous Leukemia (CML) K562 cells and induce apoptosis. Since Heat Shock Factor...