Poppy H L Lamberton
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Explore the profile of Poppy H L Lamberton including associated specialties, affiliations and a list of published articles.
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52
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Recent Articles
1.
Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic
Berger D, Park S, Crellen T, Vianney T, Kabatereine N, Cotton J, et al.
bioRxiv
. 2024 Sep;
PMID: 39257780
Mass-drug administration (MDA) of human populations using praziquantel monotherapy has become the primary strategy for controlling and potentially eliminating the major neglected tropical disease schistosomiasis. To understand how long-term MDA...
2.
Alonso S, Arinaitwe M, Atuhaire A, Nankasi A, Prada J, McIntosh E, et al.
Proc Biol Sci
. 2024 Jun;
291(2024):20240449.
PMID: 38864320
The WHO aims to eliminate schistosomiasis as a public health problem by 2030. However, standard morbidity measures poorly correlate to infection intensities, hindering disease monitoring and evaluation. This is exacerbated...
3.
Kameni M, Musaigwa F, Kamguia L, Kamdem S, Mbanya G, Lamberton P, et al.
PLoS Negl Trop Dis
. 2024 Mar;
18(3):e0012009.
PMID: 38512811
Schistosomiasis is the second most widespread parasitic disease affecting humans. A key component of today's infection control measures is the diagnosis and monitoring of infection, informing individual- and community-level treatment....
4.
Lim R, Arme T, Pedersen A, Webster J, Lamberton P
Trends Parasitol
. 2023 Oct;
39(12):1032-1049.
PMID: 37806786
The World Health Organization (WHO) recently proposed a new operational definition which designates communities with ≥10% prevalence of Schistosoma spp. infection as a persistent hotspot, when, after at least two...
5.
Kabbas-Pinango E, Arinaitwe M, van Dam G, Moses A, Namukuta A, Nankasi A, et al.
Philos Trans R Soc Lond B Biol Sci
. 2023 Aug;
378(1887):20220275.
PMID: 37598698
Over 240 million people are infected with schistosomiasis. Detecting eggs in stool using Kato-Katz thick smears (Kato-Katzs) is highly specific but lacks sensitivity. The urine-based point-of-care circulating cathodic antigen test...
6.
Mujumbusi L, Nalwadda E, Ssali A, Pickering L, Seeley J, Meginnis K, et al.
PLoS Negl Trop Dis
. 2023 Jan;
17(1):e0010687.
PMID: 36656869
Background: Schistosomiasis is a neglected tropical disease and a serious global-health problem with over 230 million people requiring treatment, of which the majority live in Africa. In Uganda, over 4...
7.
Crellen T, Haswell M, Sithithaworn P, Sayasone S, Odermatt P, Lamberton P, et al.
Proc Biol Sci
. 2023 Jan;
290(1991):20222204.
PMID: 36651047
Helminth transmission and morbidity are dependent on the number of mature parasites within a host; however, observing adult worms is impossible for many natural infections. An outstanding challenge is therefore...
8.
Clark J, Moses A, Nankasi A, Faust C, Adriko M, Ajambo D, et al.
Front Trop Dis
. 2022 Jul;
3:825721.
PMID: 35784267
Schistosomiasis is a parasitic disease affecting over 240-million people. World Health Organization (WHO) targets for Schistosoma mansoni elimination are based on Kato-Katz egg counts, without translation to the widely used,...
9.
Sun M, Gu M, Zhang J, Yu Q, Lamberton P, Lu D
PLoS Negl Trop Dis
. 2022 Jan;
16(1):e0010136.
PMID: 35030167
Background: As China is moving onto schistosomiasis elimination/eradication, diagnostic methods with both high sensitivity and specificity for Schistosoma japonicum infections in humans are urgently needed. Microscopic identification of eggs in...
10.
Trienekens S, Faust C, Besigye F, Pickering L, Tukahebwa E, Seeley J, et al.
Parasit Vectors
. 2022 Jan;
15(1):15.
PMID: 34991702
Background: Annual mass drug administration with praziquantel has reduced schistosomiasis transmission in some highly endemic areas, but areas with persistent high endemicity have been identified across sub-Saharan Africa, including Uganda....