Thomas Crellen
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Explore the profile of Thomas Crellen including associated specialties, affiliations and a list of published articles.
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29
Citations
563
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Recent Articles
1.
Wangwiwatsin A, Kulwong S, Phuyao C, Titapun A, Loilome W, Klanrit P, et al.
Wellcome Open Res
. 2025 Feb;
10:1.
PMID: 39949572
We present a genome assembly from a specimen of (liver fluke; Platyhelminthes; Trematoda; Opisthorchiida; Opisthorchiidae). The genome sequence has a total length of 627.20 megabases. Most of the assembly (97.89%)...
2.
Wongphutorn P, Kopolrat K, Worasith C, Eamudomkarn C, Hongsrichan N, Pitaksakulrat O, et al.
PLoS One
. 2024 Dec;
19(12):e0306732.
PMID: 39625913
Detection of Strogyloides-specific IgG antibodies in urine and serum has been used in diagnostic and epidemiological studies on strongyloidiasis. However, the usefulness of these assays in assessing responses to anthelmintic...
3.
Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic
Berger D, Park S, Crellen T, Vianney T, Kabatereine N, Cotton J, et al.
bioRxiv
. 2024 Sep;
PMID: 39257780
Mass-drug administration (MDA) of human populations using praziquantel monotherapy has become the primary strategy for controlling and potentially eliminating the major neglected tropical disease schistosomiasis. To understand how long-term MDA...
4.
Khuntikeo N, Thinkhamrop B, Crellen T, Eamudomkarn C, Petney T, Andrews R, et al.
Recent Results Cancer Res
. 2023 Sep;
219:27-52.
PMID: 37660330
It is known that Opisthorchis viverrini (OV) is the most significant risk factor for the development of cholangiocarcinoma (CCA); hence, it is also known as carcinogenic parasite. Effective control and...
5.
Wongphutorn P, Worasith C, Kopolrat K, Homwong C, Sithithaworn J, Eamudomkarn C, et al.
Parasit Vectors
. 2023 Aug;
16(1):298.
PMID: 37641157
Background: Detection of parasite-specific IgG in urine is a sensitive method for diagnosis of strongyloidiasis and gives similar accuracy to serum IgG. However, there are no data concerning detection of...
6.
Borlase A, Prada J, Crellen T
Philos Trans R Soc Lond B Biol Sci
. 2023 Aug;
378(1887):20220279.
PMID: 37598702
Reducing the morbidities caused by neglected tropical diseases (NTDs) is a central aim of ongoing disease control programmes. The broad spectrum of pathogens under the umbrella of NTDs lead to...
7.
Worasith C, Techasen A, Duenngai K, Intuyod K, Kopolrat K, Sithithaworn J, et al.
Am J Trop Med Hyg
. 2023 May;
109(1):159-165.
PMID: 37217166
Detection of worm antigen in urine is a sensitive diagnostic method for opisthorchiasis, particularly for light-intensity infections; however, the presence of eggs in feces is essential for validating results from...
8.
Crellen T, Haswell M, Sithithaworn P, Sayasone S, Odermatt P, Lamberton P, et al.
Proc Biol Sci
. 2023 Jan;
290(1991):20222204.
PMID: 36651047
Helminth transmission and morbidity are dependent on the number of mature parasites within a host; however, observing adult worms is impossible for many natural infections. An outstanding challenge is therefore...
9.
Worasith C, Wongphutorn P, Kopolrat K, Homwong C, Techasen A, Thanan R, et al.
Am J Trop Med Hyg
. 2022 Dec;
108(2):356-358.
PMID: 36572008
Antigen detected in urine for the diagnosis of opisthorchiasis has a low daily variation; however, the longer term variability in antigen concentrations is unknown. In this study, we prospectively monitored...
10.
Worasith C, Wongphutorn P, Homwong C, Kopolrat K, Techasen A, Thanan R, et al.
PLoS One
. 2022 Jul;
17(7):e0271553.
PMID: 35853022
Antigen detection in urine using an enzyme-linked immunosorbent assay (ELISA) is more sensitive than fecal examination for diagnosis of opisthorchiasis and for assessment of the effects of drug treatment. It...