Ponsiree Jithavech
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Explore the profile of Ponsiree Jithavech including associated specialties, affiliations and a list of published articles.
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76
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Recent Articles
1.
Li Q, Ding Y, Ou Y, Li M, Jithavech P, Buranasudja V, et al.
Curr Pharm Des
. 2023 Nov;
29(36):2867-2876.
PMID: 37957863
Background: Curcuminoids, including curcumin, desmethoxycurcumin, and bisdesmethoxycurcumin, are natural polyphenolic compounds that exhibit various biological properties, such as antioxidant, anti-inflammatory, and anticancer activities. Dysregulation of the interleukin (IL)-6-mediated Janus kinase/signal...
2.
Ratnatilaka Na Bhuket P, Jithavech P, Ongpipattanakul B, Rojsitthisak P
RSC Adv
. 2022 May;
9(8):4626-4634.
PMID: 35520191
The investigation of plasma metabolism of ester prodrugs is an important part of ADME assays during preclinical drug development. Here, we show that the metabolism including plasma stability and metabolizing...
3.
Jithavech P, Suwattananuruk P, Hasriadi , Muangnoi C, Thitikornpong W, Towiwat P, et al.
PLoS One
. 2022 Mar;
17(3):e0265689.
PMID: 35303012
Curcumin is a polyphenol compound that alleviates several neuroinflammation-related diseases including Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy and cerebral injury. However, the therapeutic efficacy of curcumin is limited by...
4.
Yuyun Y, Jithavech P, Thitikornpong W, Vajragupta O, Rojsitthisak P
Molecules
. 2021 Sep;
26(17).
PMID: 34500831
A simple, precise, and accurate reversed-phase ultra-performance liquid chromatographic (UPLC) method was developed and validated for the determination of a mycophenolic acid-curcumin (MPA-CUR) conjugate in buffer solutions. Chromatographic separation was...
5.
Jithavech P, Ratnatilaka Na Bhuket P, Supasena W, Qiu G, Ye S, Wu J, et al.
Front Pharmacol
. 2020 Dec;
11:577998.
PMID: 33312126
Liver S9 (LS9) is a nearly complete collection of all hepatic drug-metabolizing enzymes. It is a low-cost model for predicting drug metabolic activity. This study aimed to identify the suitability...
6.
Muangnoi C, Ratnatilaka Na Bhuket P, Jithavech P, Supasena W, Paraoan L, Patumraj S, et al.
Sci Rep
. 2019 Aug;
9(1):11718.
PMID: 31406217
Curcumin (Cur) has been reported to have anti-hepatocellular carcinoma activity but its poor oral bioavailability limits its further development as a chemotherapeutic agent. We synthesized previously a succinate ester prodrug...
7.
Muangnoi C, Ratnatilaka Na Bhuket P, Jithavech P, Wichitnithad W, Srikun O, Nerungsi C, et al.
Pharmaceutics
. 2019 Aug;
11(8).
PMID: 31374932
Previously, we synthesized curcumin and a succinate ester prodrug of curcumin namely curcumin diethyl disuccinate (CurDD) in the lab scale, which yielded hundred milligrams to few grams of the compounds....
8.
Muangnoi C, Jithavech P, Ratnatilaka Na Bhuket P, Supasena W, Wichitnithad W, Towiwat P, et al.
Biosci Biotechnol Biochem
. 2018 Apr;
82(8):1301-1308.
PMID: 29678124
In this work, a curcumin-diglutaric acid (CurDG) prodrug was synthesized by conjugation of curcumin with glutaric acid via an ester linkage. The water solubility, partition coefficient, release characteristics, and antinociceptive...
9.
Wichitnithad W, Jithavech P, Sanphanya K, Vicheantawatchai P, Rojsitthisak P
J Chromatogr Sci
. 2015 Jun;
53(10):1663-72.
PMID: 26084706
A fast and simple sample cleanup approach for levocetirizine in human was developed using protein precipitation coupled with LC-MS-MS. Samples were treated with 6% trichloroacetic acid in water prior to...
10.
Leelarasamee A, Rongrungruang Y, Trakulsomboon S, Pongpech P, Thanawattanawanich P, Jithavech P
J Med Assoc Thai
. 2008 Oct;
91(7):980-8.
PMID: 18839835
Background: The authors aimed to compare the bioequivalence and antibacterial activity of a generic meropenem with the original meropenem and studied its preliminary therapeutic outcome. Material And Method: A randomized,...