Pahweenvaj Ratnatilaka Na Bhuket
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Explore the profile of Pahweenvaj Ratnatilaka Na Bhuket including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ratnatilaka Na Bhuket P, Li Y, Yu S
Acc Chem Res
. 2024 May;
57(12):1649-1657.
PMID: 38795029
ConspectusFacilitated by the unique triple-helical protein structure, fibrous collagens, the principal proteins in animals, demonstrate a dual function of serving as building blocks for tissue scaffolds and as a bioactive...
2.
Luke E, Ratnatilaka Na Bhuket P, Yu S, Weiss J
J Orthop Res
. 2023 Apr;
41(11):2424-2432.
PMID: 37087677
The objective of this study was to investigate the potential of collagen hybridizing peptides (CHPs), which bind to denatured collagen, to extend the retention time of near-infrared fluorophores (NIRF) following...
3.
Ratnatilaka Na Bhuket P, Jithavech P, Ongpipattanakul B, Rojsitthisak P
RSC Adv
. 2022 May;
9(8):4626-4634.
PMID: 35520191
The investigation of plasma metabolism of ester prodrugs is an important part of ADME assays during preclinical drug development. Here, we show that the metabolism including plasma stability and metabolizing...
4.
Yuyun Y, Ratnatilaka Na Bhuket P, Supasena W, Suwattananuruk P, Praengam K, Vajragupta O, et al.
Pharmaceutics
. 2021 Jul;
13(7).
PMID: 34201974
Curcumin (CUR) has been used as adjuvant therapy for therapeutic application in the treatment of psoriasis through several mechanisms of action. Due to the poor oral bioavailability of CUR, several...
5.
Luckanagul J, Ratnatilaka Na Bhuket P, Muangnoi C, Rojsitthisak P, Wang Q, Rojsitthisak P
Polymers (Basel)
. 2021 Jan;
13(2).
PMID: 33430269
A hyaluronic acid-grafted poly(-isopropylacrylamide) (HA-pNIPAM) was synthesized as a polymeric nanogel platform for encapsulation and delivery of hydrophobic bioactive compounds using curcumin as a model drug. As demonstrated by transmission...
6.
Jithavech P, Ratnatilaka Na Bhuket P, Supasena W, Qiu G, Ye S, Wu J, et al.
Front Pharmacol
. 2020 Dec;
11:577998.
PMID: 33312126
Liver S9 (LS9) is a nearly complete collection of all hepatic drug-metabolizing enzymes. It is a low-cost model for predicting drug metabolic activity. This study aimed to identify the suitability...
7.
Ratnatilaka Na Bhuket P, Wichitnithad W, Sudtanon O, Rojsitthisak P
Heliyon
. 2020 Sep;
6(8):e04561.
PMID: 32904269
A stability-indicating reversed-phase ultra-performance liquid chromatographic (UPLC) method for quantitative analysis of curcumin diethyl disuccinate (CDD) in raw materials was developed for applications in product development and quality control. Chromatographic...
8.
Sorasitthiyanukarn F, Muangnoi C, Thaweesest W, Ratnatilaka Na Bhuket P, Jantaratana P, Rojsitthisak P, et al.
Biomolecules
. 2020 Jan;
10(1).
PMID: 31906490
Curcumin diglutaric acid-loaded polyethylene glycol-chitosan oligosaccharide-coated superparamagnetic iron oxide nanoparticles (CG-PEG-CSO-SPIONs) were fabricated by co-precipitation and optimized using a Box-Behnken statistical design in order to achieve the minimum size, optimal...
9.
Muangnoi C, Ratnatilaka Na Bhuket P, Jithavech P, Supasena W, Paraoan L, Patumraj S, et al.
Sci Rep
. 2019 Aug;
9(1):11718.
PMID: 31406217
Curcumin (Cur) has been reported to have anti-hepatocellular carcinoma activity but its poor oral bioavailability limits its further development as a chemotherapeutic agent. We synthesized previously a succinate ester prodrug...
10.
Muangnoi C, Ratnatilaka Na Bhuket P, Jithavech P, Wichitnithad W, Srikun O, Nerungsi C, et al.
Pharmaceutics
. 2019 Aug;
11(8).
PMID: 31374932
Previously, we synthesized curcumin and a succinate ester prodrug of curcumin namely curcumin diethyl disuccinate (CurDD) in the lab scale, which yielded hundred milligrams to few grams of the compounds....