Piotr Swiderski
Overview
Explore the profile of Piotr Swiderski including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
42
Citations
2295
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chen F, Zhao D, Xu Y, Zhang Y, Chen M, Pathak K, et al.
Nat Commun
. 2025 Feb;
16(1):1253.
PMID: 39893171
We reported that an acquired miR-142 deficit transforms chronic phase (CP) chronic myeloid leukemia (CML) leukemic stem cells (LSCs) into blast crisis (BC) LSCs. Given the role of miR-142 in...
2.
Zhang C, Huang R, Ren L, Martincuks A, Song J, Kortylewski M, et al.
Mol Ther Nucleic Acids
. 2024 Dec;
35(4):102357.
PMID: 39618825
Immune checkpoint blockade (ICB) therapy has significantly benefited patients with several types of solid tumors and some lymphomas. However, many of the treated patients do not have a durable clinical...
3.
Li Y, Chien S, Huang R, Herrmann A, Zhao Q, Li P, et al.
Mol Ther
. 2024 Aug;
32(10):3629-3649.
PMID: 39091030
Although CRISPR-Cas9 technology is poised to revolutionize the treatment of diseases with underlying genetic mutations, it faces some significant issues limiting clinical entry. They include low-efficiency in vivo systemic delivery...
4.
Hall J, Zhang Z, Bhattacharya S, Wang D, Alcantara M, Liang Y, et al.
Mol Ther Nucleic Acids
. 2024 Feb;
35(1):102137.
PMID: 38384444
Decoy oligodeoxynucleotides (ODNs) allow targeting undruggable transcription factors, such as STAT3, but their limited potency and lack of delivery methods hampered translation. To overcome these challenges, we conjugated a STAT3-specific...
5.
Zhang B, Zhao D, Chen F, Frankhouser D, Wang H, Pathak K, et al.
Nat Commun
. 2023 Sep;
14(1):5325.
PMID: 37658085
The mechanisms underlying the transformation of chronic myeloid leukemia (CML) from chronic phase (CP) to blast crisis (BC) are not fully elucidated. Here, we show lower levels of miR-142 in...
6.
Zhang C, Huang R, Ren L, Song J, Kortylewski M, Swiderski P, et al.
bioRxiv
. 2023 Aug;
PMID: 37645787
Immune checkpoint blockade (ICB) therapy has significantly benefited patients with several types of solid tumors and some lymphomas. However, many of the treated patients do not have durable clinical response....
7.
Hall J, Zhang Z, Wang D, Bhattacharya S, Alcantara M, Liang Y, et al.
bioRxiv
. 2023 Aug;
PMID: 37577590
Decoy-oligodeoxynucleotides (D-ODNs) can target undruggable transcription factors, such as STAT3. However, challenges in D-ODN delivery and potency hampered their translation. To overcome these limitations, we conjugated STAT3-specific D-ODN to thalidomide...
8.
Esposito C, Autiero I, Sandomenico A, Li H, Bassal M, Ibba M, et al.
Nat Commun
. 2023 Jan;
14(1):99.
PMID: 36609400
DNA methylation is a fundamental epigenetic modification regulating gene expression. Aberrant DNA methylation is the most common molecular lesion in cancer cells. However, medical intervention has been limited to the...
9.
Andrikakou P, Reebye V, Vasconcelos D, Yoon S, Voutila J, George A, et al.
Nucleic Acid Ther
. 2022 Jul;
32(6):486-496.
PMID: 35895511
Metabolic syndrome (MetS) is a pathological condition characterized by abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. Sirtuin 1 (SIRT1), a highly conserved histone deacetylase, is characterized as a key metabolic...
10.
Adamus T, Hung C, Yu C, Kang E, Hammad M, Flores L, et al.
Mol Ther Nucleic Acids
. 2022 Jan;
27:611-620.
PMID: 35036069
Tropism of neural stem cells (NSCs) to hypoxic tumor areas provides an opportunity for the drug delivery. Here, we demonstrate that NSCs effectively transport antisense oligonucleotides (ASOs) targeting oncogenic and...