Ping-Yi Wu
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Explore the profile of Ping-Yi Wu including associated specialties, affiliations and a list of published articles.
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21
Citations
412
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Recent Articles
11.
Shih Y, Sun C, Chou H, Wu T, Chen C, Wu P, et al.
Sci Rep
. 2015 Oct;
5:15259.
PMID: 26482836
Selection of escape mutants with mutations within the target sequence could abolish the antiviral RNA interference activity. Here, we investigated the impact of a pre-existing shRNA-resistant HBV variant on the...
12.
Sun C, Wu T, Chen C, Wu P, Shih Y, Tsuneyama K, et al.
Hum Gene Ther
. 2013 Jul;
24(8):739-50.
PMID: 23829557
Adeno-associated virus (AAV)-mediated RNA interference shows promise as a therapy for chronic hepatitis B virus (HBV) infection, but its low efficacy and hepatotoxicity pose major challenges. We have generated AAV...
13.
Pan W, Lo C, Chen C, Wu P, Roffler S, Shyue S, et al.
Mol Ther
. 2012 Feb;
20(5):927-37.
PMID: 22334018
Interleukin-12 (IL-12) has potent antitumor activity, but its clinical application is limited by severe systemic toxicity, which might be alleviated by the use of membrane-anchored IL-12. In the present study,...
14.
Huang Y, Fang C, Tsuneyama K, Chou H, Pan W, Shih Y, et al.
Int J Oncol
. 2011 Aug;
39(6):1511-9.
PMID: 21805030
A relevant animal model is critical for investigating the pathogenic mechanisms underlying hepatitis B virus (HBV)-induced hepatocellular carcinoma (HCC). Mice are not naturally infected by HBV, presumably due to the...
15.
Chou H, Lin X, Pan W, Wu P, Chang C, Lin T, et al.
J Immunol
. 2010 Oct;
185(9):5468-75.
PMID: 20889541
The standard hepatitis B surface Ag (HBsAg) vaccine fails to induce anti-hepatitis B surface Abs in 5-10% of healthy subjects, a phenomenon known as HBsAg nonresponsiveness, which is closely related...
16.
Lo C, Chang C, Tang S, Pan W, Fang C, Chen Y, et al.
J Gene Med
. 2010 May;
12(5):423-34.
PMID: 20440753
Background: Hepatocellular carcinoma (HCC) is one of the most difficult cancers to treat. The interleukin (IL)-12 family cytokines, including IL-12, IL-23 and IL-27, display overlapping, but not redundant, roles in...
17.
Chang C, Lo C, Shih Y, Chen Y, Wu P, Tsuneyama K, et al.
Hum Gene Ther
. 2010 Jan;
21(5):611-21.
PMID: 20064014
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, but effective therapies are still needed. The liver has been identified as an important immune organ and is heavily...
18.
Leung P, Shu S, Kenny T, Wu P, Tao M
Autoimmun Rev
. 2009 Dec;
9(5):A400-5.
PMID: 20035901
Recent advancement in immunology, molecular biology, and bioinformatics has yielded extensive information on the pathophysiological mechanisms of autoimmunity, which has greatly facilitated the identification of potential therapeutic targets and the...
19.
Leung P, Dhirapong A, Wu P, Tao M
Autoimmun Rev
. 2009 Oct;
9(3):170-4.
PMID: 19854300
Clinical treatment of autoimmune disorders presents a special challenge. For decades, most clinical regimens in autoimmunity has been largely symptomatic and non-disease specific. Although data from vigorous research has lead...
20.
Liu Q, Ji S, Wu P, Hu L, Huang X, Zhu J, et al.
Guang Pu Xue Yu Guang Pu Fen Xi
. 2009 Aug;
29(5):1227-31.
PMID: 19650459
Abstract The supported nickel phosphate precursors were prepared by incipient wetness impregnation using nickel nitrate as nickel source, diammonium hydrogen phosphate as phosphorus source, and MCM-41, MCM-48, SBA-15 and SBA-16...