Ping-Wu Zhang
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Explore the profile of Ping-Wu Zhang including associated specialties, affiliations and a list of published articles.
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23
Citations
2039
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Recent Articles
1.
Zhang P, Wan Z, Li W, Vats A, Mehta K, Fan L, et al.
J Neuroinflammation
. 2025 Jan;
22(1):20.
PMID: 39875939
Background: The retinal degenerative diseases retinitis pigmentosa (RP) and atrophic age- related macular degeneration (AMD) are characterized by vision loss from photoreceptor (PR) degeneration. Unfortunately, current treatments for these diseases...
2.
Zhang P, Zhang S, Li W, Keuthan C, Li S, Takaesu F, et al.
EBioMedicine
. 2022 Aug;
83:104225.
PMID: 36030648
Background: Though case fatality rate (CFR) is widely used to reflect COVID-19 fatality risk, its use is limited by large temporal and spatial variation. Hospital mortality rate (HMR) is also...
3.
Eldred K, Hadyniak S, Hussey K, Brenerman B, Zhang P, Chamling X, et al.
Science
. 2018 Oct;
362(6411).
PMID: 30309916
The mechanisms underlying specification of neuronal subtypes within the human nervous system are largely unknown. The blue (S), green (M), and red (L) cones of the retina enable high-acuity daytime...
4.
Welsbie D, Mitchell K, Jaskula-Ranga V, Sluch V, Yang Z, Kim J, et al.
Neuron
. 2017 Jun;
94(6):1142-1154.e6.
PMID: 28641113
Dual leucine zipper kinase (DLK) has been implicated in cell death signaling secondary to axonal damage in retinal ganglion cells (RGCs) and other neurons. To better understand the pathway through...
5.
Miller S, Zhang P, Glatzer J, Rothstein J
J Neurogenet
. 2016 Dec;
31(1-2):37-48.
PMID: 28019127
Astroglia are a morphologically diverse and highly abundant cell type in the CNS. Despite these obvious observations, astroglia still remain largely uncharacterized at the cellular and molecular level. In disease...
6.
Zhang P, Haidet-Phillips A, Pham J, Lee Y, Huo Y, Tienari P, et al.
Glia
. 2015 Aug;
64(1):63-75.
PMID: 26295203
Astrocytes are instrumental to major brain functions, including metabolic support, extracellular ion regulation, the shaping of excitatory signaling events and maintenance of synaptic glutamate homeostasis. Astrocyte dysfunction contributes to numerous...
7.
Li Y, Balasubramanian U, Cohen D, Zhang P, Mosmiller E, Sattler R, et al.
PLoS One
. 2015 Mar;
10(3):e0118266.
PMID: 25760436
Amyotrophic lateral sclerosis is a progressive disease characterized by the loss of upper and lower motor neurons, leading to paralysis of voluntary muscles. About 10% of all ALS cases are...
8.
Donnelly C, Zhang P, Pham J, Haeusler A, Heusler A, Mistry N, et al.
Neuron
. 2013 Oct;
80(2):415-28.
PMID: 24139042
A hexanucleotide GGGGCC repeat expansion in the noncoding region of the C9ORF72 gene is the most common genetic abnormality in familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia...
9.
Park J, Hu J, Milshteyn A, Zhang P, Moore C, Park S, et al.
Cell
. 2013 Aug;
154(3):637-50.
PMID: 23911326
Synaptic plasticity induced by cocaine and other drugs underlies addiction. Here we elucidate molecular events at synapses that cause this plasticity and the resulting behavioral response to cocaine in mice....
10.
Lee Y, Morrison B, Li Y, Lengacher S, Farah M, Hoffman P, et al.
Nature
. 2012 Jul;
487(7408):443-8.
PMID: 22801498
Oligodendroglia support axon survival and function through mechanisms independent of myelination, and their dysfunction leads to axon degeneration in several diseases. The cause of this degeneration has not been determined,...