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» Authors » Pim L J van der Heiden

Pim L J van der Heiden

Explore the profile of Pim L J van der Heiden including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 112
Followers 0
Related Specialties
General Medicine
Critical Care
Pharmacology
Top 10 Co-Authors
Marcus J Schultz
Laura A Buiteman-Kruizinga
Frederique Paulus
Ary Serpa Neto
Michela Botta
Erik W A Marijt
David M P van Meenen
J H Frederik Falkenburg
Paolo Pelosi
Janneke Horn
Published In
PLoS One
J Clin Med
Thromb Haemost
J Clin Virol
Crit Care Explor
Affiliations
Soon will be listed here.
Recent Articles
1.
Association of ventilation volumes, pressures and rates with the mechanical power of ventilation in patients without acute respiratory distress syndrome: exploring the impact of rate reduction
Buiteman-Kruizinga L, van Meenen D, Serpa Neto A, Mazzinari G, Bos L, van der Heiden P, et al.
Anaesthesia . 2025 Feb; PMID: 39938476
Introduction: High mechanical power is associated with mortality in patients who are critically ill and require invasive ventilation. It remains uncertain which components of mechanical power - volume, pressure or...
2.
Effects of Automated Versus Conventional Ventilation on Quality of Oxygenation-A Substudy of a Randomized Crossover Clinical Trial
Botta M, van Meenen D, van Leijsen T, Rogmans J, List S, van der Heiden P, et al.
J Clin Med . 2025 Jan; 14(1. PMID: 39797125
: Attaining adequate oxygenation in critically ill patients undergoing invasive ventilation necessitates intense monitoring through pulse oximetry (SpO) and frequent manual adjustments of ventilator settings like the fraction of inspired...
3.
Effect of automated versus conventional ventilation on mechanical power of ventilation-A randomized crossover clinical trial
Buiteman-Kruizinga L, Serpa Neto A, Botta M, List S, de Boer B, van Velzen P, et al.
PLoS One . 2024 Jul; 19(7):e0307155. PMID: 39078857
Introduction: Mechanical power of ventilation, a summary parameter reflecting the energy transferred from the ventilator to the respiratory system, has associations with outcomes. INTELLiVENT-Adaptive Support Ventilation is an automated ventilation...
4.
Effects of closed loop ventilation on ventilator settings, patient outcomes and ICU staff workloads - a systematic review
Goossen R, Schultz M, Tschernko E, Chew M, Robba C, Paulus F, et al.
Eur J Anaesthesiol . 2024 Feb; 41(6):438-446. PMID: 38385449
Background: Lung protective ventilation is considered standard of care in the intensive care unit. However, modifying the ventilator settings can be challenging and is time consuming. Closed loop modes of...
5.
Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial
van der Wal L, Grim C, Del Prado M, van Westerloo D, Boerma E, Rijnhart-de Jong H, et al.
Am J Respir Crit Care Med . 2023 Aug; 208(7):770-779. PMID: 37552556
Supplemental oxygen is widely administered to ICU patients, but appropriate oxygenation targets remain unclear. This study aimed to determine whether a low-oxygenation strategy would lower 28-day mortality compared with a...
6.
A closed-loop ventilation mode that targets the lowest work and force of breathing reduces the transpulmonary driving pressure in patients with moderate-to-severe ARDS
Buiteman-Kruizinga L, van Meenen D, Bos L, van der Heiden P, Paulus F, Schultz M
Intensive Care Med Exp . 2023 Jul; 11(1):42. PMID: 37442844
Introduction: The driving pressure (ΔP) has an independent association with outcome in patients with acute respiratory distress syndrome (ARDS). INTELLiVENT-Adaptive Support Ventilation (ASV) is a closed-loop mode of ventilation that...
7.
Closed-loop ventilation in COVID-19 patients with acute hypoxemic respiratory failure-A case series
Buiteman-Kruizinga L, van der Heiden P, Paulus F, Schultz M
Nurs Crit Care . 2023 May; 29(1):219-225. PMID: 37144426
Background: INTELLiVENT-adaptive support ventilation (ASV) is an automated closed-loop mode of invasive ventilation for use in critically ill patients. INTELLiVENT-ASV automatically adjusts, without the intervention of the caregiver, ventilator settings...
8.
Low and Highly Variable Exposure to Prophylactic LMWH Nadroparin in Critically Ill Patients: Back to the Drawing Board for Prophylactic Dosing?
Diepstraten J, van Rongen A, Zijlstra M, Kruip M, van der Heiden P, Ter Heine R
Clin Pharmacokinet . 2022 Dec; 62(2):297-305. PMID: 36581732
Background And Objective: Low-molecular-weight heparins are routinely administered to patients in the intensive care unit to prevent venous thromboembolisms. There is considerable evidence that low-molecular-weight heparin doses should be personalised...
9.
Effect of Automated Closed-loop ventilation versus convenTional VEntilation on duration and quality of ventilation in critically ill patients (ACTiVE) - study protocol of a randomized clinical trial
Botta M, Tsonas A, Sinnige J, de Bie A, Bindels A, Ball L, et al.
Trials . 2022 Apr; 23(1):348. PMID: 35461264
Background: INTELLiVENT-Adaptive Support Ventilation (ASV) is a fully automated closed-loop mode of ventilation for use in critically ill patients. Evidence for benefit of INTELLiVENT-ASV in comparison to ventilation that is...
10.
Effect of INTELLiVENT-ASV versus Conventional Ventilation on Ventilation Intensity in Patients with COVID-19 ARDS-An Observational Study
Buiteman-Kruizinga L, Mkadmi H, Serpa Neto A, Kruizinga M, Botta M, Schultz M, et al.
J Clin Med . 2021 Nov; 10(22). PMID: 34830691
Driving pressure (ΔP) and mechanical power (MP) are associated with outcomes in critically ill patients, irrespective of the presence of Acute Respiratory Distress Syndrome (ARDS). INTELLiVENT-ASV, a fully automated ventilatory...