Pierre Verrelle
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Explore the profile of Pierre Verrelle including associated specialties, affiliations and a list of published articles.
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80
Citations
1098
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Recent Articles
21.
Fouillade C, Curras-Alonso S, Giuranno L, Quelennec E, Heinrich S, Bonnet-Boissinot S, et al.
Clin Cancer Res
. 2019 Dec;
26(6):1497-1506.
PMID: 31796518
Purpose: One of the main limitations to anticancer radiotherapy lies in irreversible damage to healthy tissues located within the radiation field. "FLASH" irradiation at very high dose-rate is a new...
22.
Grandin N, Pereira B, Cohen C, Billard P, Dehais C, Carpentier C, et al.
Acta Neuropathol Commun
. 2019 Nov;
7(1):175.
PMID: 31706351
All cancer cells need to maintain functional telomeres to sustain continuous cell division and proliferation. In human diffuse gliomas, functional telomeres are maintained due either to reactivation of telomerase expression,...
23.
Biau J, Chautard E, Verrelle P, Dutreix M
Front Oncol
. 2019 Oct;
9:1009.
PMID: 31649878
Radiation therapy (RT) is widely used in cancer care strategies. Its effectiveness relies mainly on its ability to cause lethal damage to the DNA of cancer cells. However, some cancers...
24.
Court F, Boiteux E, Fogli A, Muller-Barthelemy M, Vaurs-Barriere C, Chautard E, et al.
Genome Res
. 2019 Sep;
29(10):1605-1621.
PMID: 31533980
In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. However, multiple epigenetic mechanisms, including polycomb repressive marks, contribute to gene deregulation...
25.
Biau J, Chautard E, Berthault N, De Koning L, Court F, Pereira B, et al.
Front Oncol
. 2019 Jul;
9:549.
PMID: 31275862
High grade glioma relapses occur often within the irradiated volume mostly due to a high resistance to radiation therapy (RT). Dbait (which stands for DNA strand break bait) molecules mimic...
26.
Lansonneur P, Favaudon V, Heinrich S, Fouillade C, Verrelle P, De Marzi L
Phys Med
. 2019 Apr;
60:50-57.
PMID: 31000086
Purpose: Measurements and Monte-Carlo simulations were carried out to model the dose distribution of a prototype electron beam linear accelerator (Kinetron LINAC) to determine the dose to organs in small...
27.
Patriarca A, Fouillade C, Auger M, Martin F, Pouzoulet F, Nauraye C, et al.
Int J Radiat Oncol Biol Phys
. 2018 Jul;
102(3):619-626.
PMID: 30017793
Purpose: Recent in vivo investigations have shown that short pulses of electrons at very high dose rates (FLASH) are less harmful to healthy tissues but just as efficient as conventional...
28.
Moreau J, Khalil T, Dupic G, Chautard E, Lemaire J, Magnier F, et al.
PLoS One
. 2018 Apr;
13(4):e0195608.
PMID: 29621341
In the present study, we have evaluated the efficacy and toxicity of repeated brain metastases (BM) stereotactic radiosurgery (SRS2) following local failure of a prior radiosurgical procedure (SRS1). Between December...
29.
Khalil T, Lemaire J, Dedieu V, Donnarieix D, Beatrice C, Lapeyre M, et al.
J Radiosurg SBRT
. 2018 Jan;
2(4):291-305.
PMID: 29296372
Background: The place of radiosurgery (RS) as an option in the treatment of recurrent malignant glioma is still debated on in the absence of prospective randomized trials. Objective: To assess...
30.
Foy J, Bazire L, Ortiz-Cuaran S, Deneuve S, Kielbassa J, Thomas E, et al.
BMC Med
. 2017 Sep;
15(1):165.
PMID: 28859688
Background: Radiotherapy for head and neck squamous cell carcinomas (HNSCC) is associated with a substantial morbidity and inconsistent efficacy. Human papillomavirus (HPV)-positive status is recognized as a marker of increased...