Pierre Scotney
Overview
Explore the profile of Pierre Scotney including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
583
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0
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Recent Articles
1.
Cooper M, Cherney D, Greene T, Heerspink H, Jardine M, Lewis J, et al.
J Am Soc Nephrol
. 2024 Aug;
35(11):1546-1557.
PMID: 39150859
No abstract available.
2.
Falkevall A, Mehlem A, Folestad E, Ning F, Osorio-Conles O, Radmann R, et al.
J Hepatol
. 2023 Jan;
78(5):901-913.
PMID: 36717026
Background & Aims: Hepatic steatosis is a hallmark of non-alcoholic fatty liver disease (NAFLD), a common comorbidity in type 2 diabetes mellitus (T2DM). The pathogenesis of NAFLD is complex and...
3.
Spirig R, Campbell I, Koernig S, Chen C, Lewis B, Butcher R, et al.
J Immunol
. 2018 Mar;
200(8):2542-2553.
PMID: 29531170
Activation of Fc receptors and complement by immune complexes is a common important pathogenic trigger in many autoimmune diseases and so blockade of these innate immune pathways may be an...
4.
Falkevall A, Mehlem A, Palombo I, Sahlgren B, Ebarasi L, He L, et al.
Cell Metab
. 2017 Feb;
25(3):713-726.
PMID: 28190774
Diabetic kidney disease (DKD) is the most common cause of severe renal disease, and few treatment options are available today that prevent the progressive loss of renal function. DKD is...
5.
McCaffrey K, Boo I, Owczarek C, Hardy M, Perugini M, Fabri L, et al.
J Virol
. 2016 Dec;
91(5).
PMID: 28031364
The hepatitis C virus (HCV) envelope glycoprotein E2 is the major target of broadly neutralizing antibodies and is the focus of efforts in the rational design of a universal B...
6.
Irani Y, Scotney P, Nash A, Williams K
Invest Ophthalmol Vis Sci
. 2016 Feb;
57(2):586-91.
PMID: 26886891
Purpose: The species cross-reactivity of the monoclonal antibodies infliximab, bevacizumab, and an anti-VEGF-B antibody, 2H10, in humans and rodents was determined. Methods: The binding of infliximab to human, mouse, and...
7.
Silva A, Mount A, Krstevska K, Pejoski D, Hardy M, Owczarek C, et al.
J Immunol
. 2015 Feb;
194(5):2199-207.
PMID: 25646304
The development of therapeutic vaccines for treatment of established cancer has proven challenging. Cancer vaccines not only need to induce a robust tumor Ag-specific immune response but also need to...
8.
Broughton S, Hercus T, Hardy M, McClure B, Nero T, Dottore M, et al.
Cell Rep
. 2014 Jul;
8(2):410-9.
PMID: 25043189
Interleukin-3 (IL-3) is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Here, we report the crystal structure of the IL-3 receptor α...
9.
Edwards K, Huynh H, Prasad R, McDonald A, Hardy M, Scotney P, et al.
J Immunol Methods
. 2014 Apr;
407:48-57.
PMID: 24704819
Interleukin-13 (IL-13) is a cytokine implicated in airway diseases such as asthma and idiopathic pulmonary fibrosis. IL-13 signals through a heterodimeric receptor complex consisting of IL-13Rα1 and IL-4Rα, known as...
10.
Hagberg C, Mehlem A, Falkevall A, Muhl L, Fam B, Ortsater H, et al.
Nature
. 2012 Oct;
490(7420):426-30.
PMID: 23023133
The prevalence of type 2 diabetes is rapidly increasing, with severe socioeconomic impacts. Excess lipid deposition in peripheral tissues impairs insulin sensitivity and glucose uptake, and has been proposed to...