Pierangelo Torquato
Overview
Explore the profile of Pierangelo Torquato including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
478
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Recent Articles
1.
Torquato P, Giusepponi D, Bartolini D, Barola C, Marinelli R, Sebastiani B, et al.
Free Radic Biol Med
. 2021 Sep;
176:142-148.
PMID: 34562608
Sample manipulation for storage and storage itself, interfere with the stability of labile lipids in human plasma, including vitamin E (α-tocopherol), polyunsaturated fatty acids (PUFAs), and their enzymatic and free...
2.
Marinelli R, Torquato P, Bartolini D, Mas-Bargues C, Bellezza G, Gioiello A, et al.
J Biol Chem
. 2020 Jul;
295(33):11866-11876.
PMID: 32616652
Garcinoic acid (GA or δ-T3-13'COOH), is a natural vitamin E metabolite that has preliminarily been identified as a modulator of nuclear receptors involved in β-amyloid (Aβ) metabolism and progression of...
3.
Bartolini D, De Franco F, Torquato P, Marinelli R, Cerra B, Ronchetti R, et al.
J Med Chem
. 2020 Mar;
63(7):3701-3712.
PMID: 32160459
Pregnane X receptor (PXR) is a master xenobiotic-sensing transcription factor and a validated target for immune and inflammatory diseases. The identification of chemical probes to investigate the therapeutic relevance of...
4.
Svegliati-Baroni G, Pierantonelli I, Torquato P, Marinelli R, Ferreri C, Chatgilialoglu C, et al.
Free Radic Biol Med
. 2019 Jun;
144:293-309.
PMID: 31152791
Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease worldwide (about 25% of the general population) and 3-5% of patients develop non-alcoholic steatohepatitis (NASH), characterized...
5.
Bartolini D, Wang Y, Zhang J, Giustarini D, Rossi R, Wang G, et al.
PLoS One
. 2019 Apr;
14(4):e0205626.
PMID: 31034521
2,2'-diselenyldibenzoic acid (DSBA) is a chemical probe produced to explore the pharmacological properties of diphenyldiselenide-derived agents with seleno-hormetic activity undergoing preclinical development. The present study was designed to verify in...
6.
Giusepponi D, Galarini R, Barola C, Torquato P, Bartolini D, Moretti S, et al.
Free Radic Biol Med
. 2019 Apr;
144:134-143.
PMID: 31009660
The role of vitamin E in both enzymatic and free radical-dependent metabolism of polyunsaturated fatty acids (PUFAs) has been well demonstrated. This study proposed a new LC-MS/MS method to quantify...
7.
Torquato P, Giusepponi D, Alisi A, Galarini R, Bartolini D, Piroddi M, et al.
Sci Rep
. 2019 Feb;
9(1):2045.
PMID: 30765737
Two recent randomized controlled trials demonstrated improved radiographic, histological and hepatometabolic cues of non-alcoholic steatohepatitis (NASH) in pediatric patients treated with the ω-3 fatty acid docosahexaenoic acid (DHA) in combination...
8.
Ambrogini P, Torquato P, Bartolini D, Albertini M, Lattanzi D, Di Palma M, et al.
Biochim Biophys Acta Mol Basis Dis
. 2019 Feb;
1865(6):1098-1112.
PMID: 30703511
Glutamate-mediated excitotoxicity, neuroinflammation, and oxidative stress are common underlying events in neurodegeneration. This pathogenic "triad" characterizes the neurobiology of epilepsy, leading to seizure-induced cell death, increased susceptibility to neuronal synchronization...
9.
Scire A, Cianfruglia L, Minnelli C, Bartolini D, Torquato P, Principato G, et al.
Biofactors
. 2018 Dec;
45(2):152-168.
PMID: 30561781
Glutathione is considered the major non-protein low molecular weight modulator of redox processes and the most important thiol reducing agent of the cell. The biosynthesis of glutathione occurs in the...
10.
Torquato P, Bartolini D, Giusepponi D, Piroddi M, Sebastiani B, Saluti G, et al.
Free Radic Biol Med
. 2018 Dec;
131:115-125.
PMID: 30508576
Lipid peroxidation is one of the earliest pathogenic events of non-alcoholic fatty liver disease (NAFLD). In this context, an increased oxidation of the lipoperoxyl radical scavenger α-tocopherol (α-TOH) should occur...