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Pien Lof

Explore the profile of Pien Lof including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 12
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Recent Articles
1.
Medina J, Annapragada A, Lof P, Short S, Bartolomucci A, Mathios D, et al.
Cancer Discov . 2024 Sep; 15(1):105-118. PMID: 39345137
There is an unmet need for effective ovarian cancer screening and diagnostic approaches that enable earlier-stage cancer detection and increased overall survival. We have developed a high-performing accessible approach that...
2.
Lof P, van Soolingen N, Piek J, Aarts J, Retel V, Bukman M, et al.
Gynecol Oncol . 2024 Jun; 187:227-234. PMID: 38823307
Objective: Treatment of advanced-stage ovarian cancer contains cytoreductive surgery (CRS) and chemotherapy. Achieving successful CRS (≤ 1 cm residual disease) is prognostically important, but may not be feasible peri-operatively while...
3.
Gaillard D, Lof P, Sistermans E, Mokveld T, Horlings H, Mom C, et al.
Int J Gynecol Cancer . 2024 Feb; 34(5):713-721. PMID: 38388177
Objective: To assess the feasibility of scalable, objective, and minimally invasive liquid biopsy-derived biomarkers such as cell-free DNA copy number profiles, human epididymis protein 4 (HE4), and cancer antigen 125...
4.
Lof P, Engelhardt E, van Gent M, Mom C, Rosier-van Dunne F, van Baal W, et al.
Int J Gynecol Cancer . 2023 Jan; 33(1):74-82. PMID: 36600495
Objectives: In patients with an ovarian mass, a risk of malignancy assessment is used to decide whether referral to an oncology hospital is indicated. Risk assessment strategies do not perform...
5.
Olsen M, Lof P, Stiekema A, van den Broek D, Wilthagen E, Bossuyt P, et al.
Acta Obstet Gynecol Scand . 2021 Jul; 100(10):1788-1799. PMID: 34212386
Introduction: Many women with benign pelvic masses, suspected of ovarian cancer, are unnecessarily referred for treatment at specialized centers. There is an unmet clinical need to improve diagnostic assessment in...
6.
Lof P, van de Vrie R, Korse C, van Driel W, van Gent M, Karlsen M, et al.
Int J Gynecol Cancer . 2019 Sep; 29(8):1304-1310. PMID: 31515411
Background: Presence of residual disease after cytoreductive surgery is an important negative prognostic factor for patients with advanced stage epithelial ovarian cancer. Surgery is of limited benefit when the diameter...
7.
Bruikman C, de Ronde M, Amin A, Levy S, Lof P, de Ruijter U, et al.
Heart . 2019 Aug; 106(3):228-232. PMID: 31422358
Objective: Sudden cardiac death (SCD) in families with premature atherosclerosis (PAS) is generally attributed to lethal arrhythmias during myocardial infarction. Yet, such arrhythmias may also arise from non-ischaemic inherited susceptibility....