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Phuong Linh Nguyen

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Articles 18
Citations 136
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Recent Articles
1.
Nguyen P, Jung J, Park J, Sim S
BMC Plant Biol . 2025 Feb; 25(1):146. PMID: 39905314
Background: The Citrus species are major fruit crops cultivated in the world and have complex genetic relationships due to sexual comparability between Citrus and related genera. Of these, satsuma mandarin...
2.
Liu B, Nguyen P, Yu H, Li X, Wang H, Nguyen T, et al.
Acta Pharm Sin B . 2024 Sep; 14(8):3661-3679. PMID: 39220874
Non-alcoholic steatohepatitis (NASH), an advanced form of non-alcoholic fatty liver disease (NAFLD), has emerged as the leading cause of liver failure and related death. Currently, no medication is specifically approved...
3.
Liu B, Nguyen P, Yu H, Li X, Wang H, Price J, et al.
J Nanobiotechnology . 2023 Sep; 21(1):352. PMID: 37770932
Background: Macrophages are highly plastic innate immune cells that play key roles in host defense, tissue repair, and homeostasis maintenance. In response to divergent stimuli, macrophages rapidly alter their functions...
4.
Bao L, Baecker D, Dung D, Phuong Nhung N, Thi Thuan N, Nguyen P, et al.
Molecules . 2023 Apr; 28(8). PMID: 37110831
Multi-target drug development has become an attractive strategy in the discovery of drugs to treat of Alzheimer's disease (AzD). In this study, for the first time, a rule-based machine learning...
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Bui B, Nguyen P, Lee K, Cho J
Cancers (Basel) . 2022 Dec; 14(24). PMID: 36551540
Hypoxia-inducible factor-1 (HIF-1) is a key transcription factor that regulates the transcription of many genes that are responsible for the adaptation and survival of tumor cells in hypoxic environments. Over...
7.
Bui B, Nguyen P, Thu Do H, Cho J
J Ginseng Res . 2022 Oct; 46(6):819-829. PMID: 36312738
Background: Anxiolytic properties of Korean Red Ginseng (KRG) have been previously reported. However, the exact mechanism(s) of action remains to be elucidated. The present study investigated the effect of KRG...
8.
Nguyen N, Duong M, Bui B, Nguyen P, Chen X, Cho J, et al.
Int J Mol Sci . 2022 Sep; 23(18). PMID: 36142500
Our structure-based virtual screening of the FDA-approved drug library has revealed that sonidegib, a smoothened antagonist clinically used to treat basal cell carcinoma, is a potential c-Jun N-terminal kinase 3...
9.
Nguyen P, Elkamhawy A, Choi Y, Lee C, Lee K, Cho J
Int J Mol Sci . 2022 Sep; 23(17). PMID: 36077298
Pharmacological inhibition of the enzyme activity targeting carbonic anhydrases (CAs) demonstrated antiglaucoma and anticancer effects through pH control. Recently, we reported a series of indole-based benzenesulfonamides as potent CA inhibitors....
10.
Nguyen N, Duong M, Nguyen P, Bui B, Ahn H, Cho J
Biomol Ther (Seoul) . 2022 Aug; 30(5):455-464. PMID: 35993250
Efonidipine, a calcium channel blocker, is widely used for the treatment of hypertension and cardiovascular diseases. In our preliminary study using structure-based virtual screening, efonidipine was identified as a potential...