Phillip H Horne
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Explore the profile of Phillip H Horne including associated specialties, affiliations and a list of published articles.
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12
Citations
198
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Recent Articles
1.
Horne P, Lampe L, Nguyen J, Herzog R, Albert T
J Bone Joint Surg Am
. 2016 Jul;
98(14):1206-14.
PMID: 27440569
Background: Developmental cervical stenosis of the spinal canal predisposes patients to neural compression and loss of function. The Torg-Pavlov ratio has been shown to provide high sensitivity but low specificity...
2.
Zimmerer J, Horne P, Fisher M, Pham T, Lunsford K, Ringwald B, et al.
Transplantation
. 2016 Jul;
100(9):1907-15.
PMID: 27379551
Background: The liver immune environment is tightly regulated to balance immune activation with immune tolerance. Understanding the dominant immune pathways initiated in the liver is important because the liver is...
3.
Horne P, Jennings J, DeOrio J, Easley M, Nunley J, Adams S
Foot Ankle Int
. 2015 Feb;
36(6):611-6.
PMID: 25712115
Background: There is little evidence regarding the incidence of symptomatic venous thromboembolism (VTE) following total ankle arthroplasty (TAA) to allow formulation of treatment recommendations. The purpose of this study was...
4.
Furman B, Mangiapani D, Zeitler E, Bailey K, Horne P, Huebner J, et al.
Arthritis Res Ther
. 2014 Jun;
16(3):R134.
PMID: 24964765
Introduction: Post-traumatic arthritis (PTA) is a progressive, degenerative response to joint injury, such as articular fracture. The pro-inflammatory cytokines, interleukin 1(IL-1) and tumor necrosis factor alpha (TNF-α), are acutely elevated...
5.
Zimmerer J, Horne P, Fiessinger L, Fisher M, Pham T, Saklayen S, et al.
Transplantation
. 2012 Dec;
94(11):1103-10.
PMID: 23222736
Background: Liver parenchymal cell allografts initiate both CD4-dependent and CD4-independent, CD8(+) T cell-mediated acute rejection pathways. The magnitude of allospecific CD8(+) T cell in vivo cytotoxic effector function is maximal...
6.
Zimmerer J, Horne P, Fiessinger L, Fisher M, Jayashankar K, Garcia S, et al.
Cell Transplant
. 2012 Oct;
22(7):1157-69.
PMID: 23069206
Allospecific T memory cell responses in transplant recipients arise from environmental exposure to previous transplantation or cross-reactive heterologous immunity. Unfortunately, these memory responses pose a significant barrier to the survival...
7.
Horne P, Olson S
Curr Rev Musculoskelet Med
. 2011 Jun;
4(3):139-45.
PMID: 21713379
Total hip arthroplasty is a successful procedure for treatment of painful hip arthritides. A large volume of literature is devoted to the patient outcomes and complication profiles of the commonly...
8.
Horne P, Lunsford K, Walker J, Koester M, Bumgardner G
Cell Transplant
. 2008 Dec;
17(7):829-44.
PMID: 19044209
As novel acute allograft rejection mechanisms are being discovered, determining the conditions that promote or subvert these distinct rejection pathways is important to interpret the clinical relevance of these pathways...
9.
Horne P, Zimmerer J, Fisher M, Lunsford K, Nadasdy G, Nadasdy T, et al.
J Immunol
. 2008 Jul;
181(2):1224-31.
PMID: 18606676
Despite the recognition that humoral rejection is an important cause of allograft injury, the mechanism of Ab-mediated injury to allograft parenchyma is not well understood. We used a well-characterized murine...
10.
Horne P, Koester M, Jayashankar K, Lunsford K, Dziema H, Bumgardner G
J Immunol
. 2007 Jun;
179(1):80-8.
PMID: 17579024
The role of CD4+ T cells in promoting CD8+ T cell effector activity in response to transplant Ags in vivo has not been reported. We used a hepatocellular allograft model...