Philippe Poussier
Overview
Explore the profile of Philippe Poussier including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
409
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Recent Articles
1.
Paun A, Yau C, Meshkibaf S, Daigneault M, Marandi L, Mortin-Toth S, et al.
Sci Immunol
. 2019 Feb;
4(32).
PMID: 30709843
Microbiome sequence analyses have suggested that changes in gut bacterial composition are associated with autoimmune disease in humans and animal models. However, little is known of the mechanisms through which...
2.
Sarmiento J, Wallis R, Ning T, Marandi L, Chao G, Veillette A, et al.
J Immunol
. 2014 Dec;
194(2):615-29.
PMID: 25505293
The R620W variant of PTPN22 is one of the major genetic risk factors for several autoimmune disorders including type 1 diabetes (T1D) in humans. In the BioBreeding T1D-prone (BBDP) rat,...
3.
Chao G, Wallis R, Marandi L, Ning T, Sarmiento J, Paterson A, et al.
J Immunol
. 2014 Mar;
192(8):3645-53.
PMID: 24646746
The autoimmune diabetic syndrome of the BioBreeding diabetes-prone (BBDP) rat is a polygenic disease that resembles in many aspects human type 1 diabetes (T1D). A successful approach to gain insight...
4.
Patrick C, Wang G, Lefebvre D, Crookshank J, Sonier B, Eberhard C, et al.
Diabetes
. 2013 Jan;
62(6):2036-47.
PMID: 23349499
We are exposed to millions of microbial and dietary antigens via the gastrointestinal tract, which likely play a key role in type 1 diabetes (T1D). We differentiated the effects of...
5.
Xiong X, Frank D, Robertson C, Hung S, Markle J, Canty A, et al.
PLoS One
. 2012 May;
7(4):e36009.
PMID: 22558305
With the advent of high through-put sequencing (HTS), the emerging science of metagenomics is transforming our understanding of the relationships of microbial communities with their environments. While metagenomics aims to...
6.
Ilangumaran S, Gagnon J, LeBlanc C, Poussier P, Ramanathan S
Immunol Lett
. 2010 May;
132(1-2):12-7.
PMID: 20438760
Mice lacking suppressor of cytokine signaling 1 (SOCS1) accumulate CD8(+) T lymphocytes in the thymus and in the periphery. Whereas IL-7 and IL-15 promote the generation of CD8 single positive...
7.
8.
Wallis R, Wang K, Marandi L, Hsieh E, Ning T, Chao G, et al.
Diabetes
. 2009 Jan;
58(4):1007-17.
PMID: 19168599
Objective: Two type 1 diabetes susceptibility genes have been identified in the spontaneously diabetic biobreeding diabetes-prone (BBDP) rat, the major histocompatibility complex (MHC) (RT1) class II u haplotype (Iddm1) and...
9.
Ilangumaran S, Forand-Boulerice M, Bousquet S, Savard A, Rocheleau P, Chen X, et al.
Mol Immunol
. 2008 Nov;
46(6):1256-9.
PMID: 19007993
The recessive lyp allele, which harbors a defective gimap5 (GTPase of immunity-associated nucleotide binding protein 5) gene, causes spontaneous apoptosis of T lymphocytes in the biobreeding diabetes-prone strain of rats....
10.
Hadjiyanni I, Baggio L, Poussier P, Drucker D
Endocrinology
. 2007 Dec;
149(3):1338-49.
PMID: 18063685
Activation of the glucagon-like peptide-1 receptor (GLP-1R) is associated with expansion of beta-cell mass due to stimulation of cell proliferation and induction of antiapoptotic pathways coupled to beta-cell survival. Although...