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Philippe Coullin

Explore the profile of Philippe Coullin including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 468
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Recent Articles
1.
Nguyen N, Zhang L, Reddy R, Dery C, Arseneau J, Cheung A, et al.
J Med Genet . 2014 Aug; 51(9):623-34. PMID: 25097207
Background: Hydatidiform mole (HM) is a human pregnancy with excessive trophoblastic proliferation and abnormal embryonic development that may be sporadic or recurrent. In the sporadic form, the HM phenotype is...
2.
Candelier J, Frappart L, Diatta A, Yadaden T, Cisse M, Afoutou J, et al.
Virchows Arch . 2013 May; 462(6):653-63. PMID: 23681114
Trophoblast cell adhesion and migration are carefully coordinated during normal placental development. We have compared the expression of three adhesion molecules, E-cadherin, β-catenin, and Lewis x, by immunohistochemistry during normal...
3.
Candelier J, Frappart L, Yadaden T, Poaty H, Picard J, Prevot S, et al.
Pathol Oncol Res . 2012 Oct; 19(2):217-27. PMID: 23065465
Abnormal trophoblast differentiation is the main cause of gestational trophoblast diseases in the case of hydatidiform moles and choriocarcinomas. Here we investigated the expression patterns of two gene products, p16...
4.
Poaty H, Coullin P, Leguern E, Dessen P, Valent A, Afoutou J, et al.
Bull Cancer . 2012 Aug; 99(9):827-43. PMID: 22877883
The complete hydatidiform mole (CHM), a gestational trophoblastic disease, is usually caused by the development of an androgenic egg whose genome is exclusively paternal. Due to parental imprinting, only trophoblasts...
5.
Poaty H, Coullin P, Peko J, Dessen P, Diatta A, Valent A, et al.
PLoS One . 2012 Jan; 7(1):e29426. PMID: 22253721
Eleven samples of DNA from choriocarcinomas were studied by high resolution CGH-array 244 K. They were studied after histopathological confirmation of the diagnosis, of the androgenic etiology and after a...
6.
Slim R, Coullin P, Diatta A, Chebaro W, Courtin D, Abdelhak S, et al.
Mol Hum Reprod . 2011 Sep; 18(1):52-6. PMID: 21948117
Gestational choriocarcinomas are malignant tumors of trophoblastic cells that affect 5-25% of women with sporadic hydatidiform moles (HMs) depending on countries and studies. Nucleotide binding and oligomerization domain-like receptor protein...
7.
Messaed C, Chebaro W, Di Roberto R, Rittore C, Cheung A, Arseneau J, et al.
J Med Genet . 2011 Jun; 48(8):540-8. PMID: 21659348
Background: NLRP7 mutations are responsible for recurrent molar pregnancies and associated reproductive wastage. To investigate the role of NLRP7 in sporadic moles and other forms of reproductive wastage, the authors...
8.
Choufani S, Shapiro J, Susiarjo M, Butcher D, Grafodatskaya D, Lou Y, et al.
Genome Res . 2011 Feb; 21(3):465-76. PMID: 21324877
Imprinted genes are critical for normal human growth and neurodevelopment. They are characterized by differentially methylated regions (DMRs) of DNA that confer parent of origin-specific transcription. We developed a new...
9.
Noguer-Dance M, Abu-Amero S, Al-Khtib M, Lefevre A, Coullin P, Moore G, et al.
Hum Mol Genet . 2010 Jul; 19(18):3566-82. PMID: 20610438
Imprinted genes play crucial roles in mammalian development and disruption of their expression is associated with many human disorders including tumourigenesis; yet, the actual number of imprinted genes in the...
10.
Deveault C, Qian J, Chebaro W, Ao A, Gilbert L, Mehio A, et al.
Hum Mol Genet . 2008 Dec; 18(5):888-97. PMID: 19066229
Hydatidiform mole is an aberrant pregnancy with abnormal embryonic development and hydropic placental villi. Common moles are sporadic, not recurrent and affect one in every 1500 pregnancies in Western societies....