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Philippe Chouvarine

Explore the profile of Philippe Chouvarine including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 718
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Recent Articles
11.
Hamberger F, Legchenko E, Chouvarine P, Mederacke Y, Taubert R, Meier M, et al.
Front Cardiovasc Med . 2022 Apr; 9:862330. PMID: 35369312
Hepatic congestion occurs in patients with right heart failure and can ultimately lead to liver fibrosis or cardiac cirrhosis. Elevated pulmonary arterial pressure is found in patients with hepatic congestion....
12.
Diekmann F, Legchenko E, Chouvarine P, Lichtinghagen R, Bertram H, Happel C, et al.
Front Cardiovasc Med . 2021 Dec; 8:794549. PMID: 34957265
Interleukin-7 (IL-7) secures B cell maturation, regulatory T and natural killer (NK) cell survival, and homeostasis, all of which are important for beneficial immunomodulation in pulmonary arterial hypertension (PAH). However,...
13.
Hansmann G, Diekmann F, Chouvarine P, Ius F, Carlens J, Schwerk N, et al.
J Heart Lung Transplant . 2021 Dec; 41(2):187-198. PMID: 34955331
Background: We investigated whether RV function recovers in children with pulmonary arterial hypertension (PAH) and RV failure undergoing lung transplantation (LuTx). Methods: Prospective observational study of 15 consecutive children, 1.9...
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Chouvarine P, Antic Z, Lentes J, Schroder C, Alten J, Bruggemann M, et al.
Cancers (Basel) . 2021 Nov; 13(22). PMID: 34830809
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common cancer in children, and significant progress has been made in diagnostics and the treatment of this disease based on the...
16.
Chouvarine P, Hansmann G
STAR Protoc . 2021 Sep; 2(3):100769. PMID: 34485938
Total RNA sequencing allows capturing of long non-coding and circular RNA along with mRNA. Additional sequencing of micro RNA (miRNA), using libraries with shorter fragments, provides the means to characterize...
17.
Diekmann F, Chouvarine P, Sallmon H, Meyer-Kobbe L, Kieslich M, Plouffe B, et al.
Int J Mol Sci . 2021 Aug; 22(16). PMID: 34445297
Pulmonary arterial hypertension (PAH) is a progressive condition with an unmet need for early diagnosis, better monitoring, and risk stratification. The receptor for advanced glycation end products (RAGE) is activated...
18.
Chouvarine P, Photiadis J, Cesnjevar R, Scheewe J, Bauer U, Pickardt T, et al.
iScience . 2021 Mar; 24(3):102232. PMID: 33786422
Right ventricular hypertrophy (RVH) occurs in high pressure afterload, e.g., tetralogy of Fallot/pulmonary stenosis (TOF/PS). Such RVH is associated with alterations in energy metabolism, neurohormonal and epigenetic dysregulation (e.g., microRNA),...
19.
Manica M, Kim H, Mathis R, Chouvarine P, Rutishauser D, De Vargas Roditi L, et al.
NPJ Syst Biol Appl . 2020 Aug; 6(1):27. PMID: 32843649
Knowledge about the clonal evolution of a tumor can help to interpret the function of its genetic alterations by identifying initiating events and events that contribute to the selective advantage...
20.
Hansmann G, Meinel K, Bukova M, Chouvarine P, Wahlander H, Koestenberger M
J Heart Lung Transplant . 2020 May; 39(7):695-706. PMID: 32362477
Background: The European Pediatric Pulmonary Vascular Disease Network (EPPVDN) investigated the safety and efficacy of add-on selexipag, an oral prostacyclin receptor agonist approved for pulmonary arterial hypertension (PAH) in adults,...