Philipp Walch
Overview
Explore the profile of Philipp Walch including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
220
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Recent Articles
1.
Bernaleau L, Drobek M, Blank F, Walch P, Delacretaz M, Drobek A, et al.
J Exp Med
. 2024 Dec;
222(3).
PMID: 39656203
Toll-like receptors (TLRs) are central to initiate immune responses against invading pathogens. To ensure host defense while avoiding aberrant activation leading to pathogenic inflammation and autoimmune diseases, TLRs are tightly...
2.
Walch P, Broz P
Nat Commun
. 2024 Oct;
15(1):8595.
PMID: 39366977
The broadening of accessible methodologies has enabled mechanistic insights into single-pathogen infections, yet the molecular mechanisms underlying co-infections remain largely elusive, despite their clinical frequency and relevance, generally exacerbating symptom...
3.
Birk M, Walch P, Baykara T, Sefried S, Amelang J, Buerova E, et al.
Eur J Cell Biol
. 2024 Aug;
103(4):151448.
PMID: 39128247
Intracellular bacterial pathogens hijack the protein machinery of infected host cells to evade their defenses and cultivate a favorable intracellular niche. The intracellular pathogen Salmonella enterica subsp. Typhimurium (STm) achieves...
4.
Ramos S, Hartenian E, Santos J, Walch P, Broz P
EMBO J
. 2024 Feb;
43(7):1164-1186.
PMID: 38396301
Ferroptosis is a regulated form of necrotic cell death caused by iron-dependent accumulation of oxidized phospholipids in cellular membranes, culminating in plasma membrane rupture (PMR) and cell lysis. PMR is...
5.
Walch P, Selkrig J, Knodler L, Rettel M, Stein F, Fernandez K, et al.
Cell Host Microbe
. 2021 Jul;
29(8):1316-1332.e12.
PMID: 34237247
Intracellular bacterial pathogens inject effector proteins to hijack host cellular processes and promote their survival and proliferation. To systematically map effector-host protein-protein interactions (PPIs) during infection, we generated a library...
6.
Selkrig J, Stanifer M, Mateus A, Mitosch K, Barrio-Hernandez I, Rettel M, et al.
Mol Syst Biol
. 2021 Feb;
17(2):e10188.
PMID: 33590968
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global threat to human health and has compromised economic stability. In addition to the development of an effective vaccine, it...
7.
Manbachi A, Kreamer-Tonin K, Walch P, Gamo N, Khoshakhlagh P, Zhang Y, et al.
Ann Biomed Eng
. 2017 Oct;
46(1):1-13.
PMID: 29019076
Following the footprints of Bill Gates, Steve Jobs and Mark Zuckerberg, there has been a misconception that students are better off quitting their studies to bring to life their ideas,...
8.
Naseer S, Manbachi A, Samandari M, Walch P, Gao Y, Zhang Y, et al.
Biofabrication
. 2017 Feb;
9(1):015020.
PMID: 28195834
Acoustic force patterning is an emerging technology that provides a platform to control the spatial location of cells in a rapid, accurate, yet contactless manner. However, very few studies have...
9.
Zhang Y, Davoudi F, Walch P, Manbachi A, Luo X, DellErba V, et al.
Lab Chip
. 2016 Oct;
16(21):4097-4105.
PMID: 27722710
Pathologic thrombosis kills more people than cancer and trauma combined; it is associated with significant disability and morbidity, and represents a major healthcare burden. Despite advancements in medical therapies and...
10.
Nadler W, Berg R, Walch P, Hanke S, Baalmann M, Kerner A, et al.
Anal Bioanal Chem
. 2015 Oct;
408(8):2055-67.
PMID: 26493978
Cysteine is unique among the proteinogenic amino acids due to its ability to form disulfide bonds. While this property is of vital importance for protein structures and biological processes, it...