Philipp S Orekhov
Overview
Explore the profile of Philipp S Orekhov including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
137
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Recent Articles
1.
Andreev G, Kovalenko M, Bozdaganyan M, Orekhov P
J Phys Chem B
. 2024 Mar;
128(13):3211-3219.
PMID: 38514440
Binding site prediction is a crucial step in understanding protein-ligand and protein-protein interactions (PPIs) with broad implications in drug discovery and bioinformatics. This study introduces Colabind, a robust, versatile, and...
2.
Ayala R, Moiseenko A, Chen T, Kulikov E, Golomidova A, Orekhov P, et al.
Nat Commun
. 2023 Dec;
14(1):8205.
PMID: 38081816
The T5 family of viruses are tailed bacteriophages characterized by a long non-contractile tail. The bacteriophage DT57C is closely related to the paradigmal T5 phage, though it recognizes a different...
3.
Bozdaganyan M, Shaitan K, Kirpichnikov M, Sokolova O, Orekhov P
Viruses
. 2022 Feb;
14(2).
PMID: 35215888
Currently, SARS-CoV-2 causing coronavirus disease 2019 (COVID-19) is responsible for one of the most deleterious pandemics of our time. The interaction between the ACE2 receptors at the surface of human...
4.
Orekhov P, Bozdaganyan M, Voskoboynikova N, Mulkidjanian A, Karlova M, Yudenko A, et al.
Nanomaterials (Basel)
. 2022 Feb;
12(3).
PMID: 35159706
Amphiphilic copolymers consisting of alternating hydrophilic and hydrophobic units account for a major recent methodical breakthrough in the investigations of membrane proteins. Styrene-maleic acid (SMA), diisobutylene-maleic acid (DIBMA), and related...
5.
Ryzhykau Y, Vlasov A, Orekhov P, Rulev M, Rogachev A, Vlasova A, et al.
Acta Crystallogr D Struct Biol
. 2021 Nov;
77(Pt 11):1386-1400.
PMID: 34726167
Membrane proteins (MPs) play vital roles in the function of cells and are also major drug targets. Structural information on proteins is vital for understanding their mechanism of function and...
6.
Bozdaganyan M, Orekhov P
Membranes (Basel)
. 2021 Jun;
11(6).
PMID: 34072597
The search for new formulations for transdermal drug delivery (TDD) is an important field in medicine and cosmetology. Molecules with specific physicochemical properties which can increase the permeability of active...
7.
Ryzhykau Y, Orekhov P, Rulev M, Vlasov A, Melnikov I, Volkov D, et al.
Sci Rep
. 2021 May;
11(1):10774.
PMID: 34031444
Two-component systems (TCS) are widespread signaling systems present in all domains of life. TCS typically consist of a signal receptor/transducer and a response regulator. The receptors (histidine kinases, chemoreceptors and...
8.
Vasyuchenko E, Orekhov P, Armeev G, Bozdaganyan M
Pharmaceutics
. 2021 Jan;
13(1).
PMID: 33430205
The cutaneous delivery route currently accounts for almost 10% of all administered drugs and it is becoming more common. Chemical penetration enhancers (CPEs) increase the transport of drugs across skin...
9.
Efimova V, Isaeva L, Orekhov P, Bozdaganyan M, Rubtsov M, Novikova L
J Biotechnol
. 2020 Nov;
325:186-195.
PMID: 33157198
Cytochrome P450scc system performs the first rate-limiting stage of steroidogenesis in mammals. The bovine P450scc system was reconstructed in Saccharomyces cerevisiae, using a foot-and-mouth disease virus 2A peptide (F2A)-based construct,...
10.
Aliper A, Bozdaganyan M, Sarkisova V, Veviorsky A, Ozerov I, Orekhov P, et al.
Aging (Albany NY)
. 2020 Aug;
12(15):15741-15755.
PMID: 32805729
The search for radioprotectors is an ambitious goal with many practical applications. Particularly, the improvement of human radioresistance for space is an important task, which comes into view with the...