Philip Overend
Overview
Explore the profile of Philip Overend including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
138
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0
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Recent Articles
1.
Johnson M, Serra Traynor C, Vishwanathan K, Overend P, Hartmaier R, Markovets A, et al.
Clin Pharmacol Ther
. 2023 Nov;
115(2):349-360.
PMID: 38010260
This exploratory, post hoc analysis aimed to model circulating tumor DNA (ctDNA) dynamics and predict disease progression in patients with treatment-naïve locally advanced/metastatic epidermal growth factor receptor mutation (EGFRm)-positive non-small...
2.
Ahn M, Kim D, Cho B, Kim S, Lee J, Ahn J, et al.
Lancet Respir Med
. 2017 Oct;
5(11):891-902.
PMID: 29056570
Background: CNS metastases-including brain and leptomeningeal metastases-from epidermal growth factor receptor (EGFR)-mutant non-small-cell lung cancer (NSCLC) are associated with poor prognosis. AZD3759 is a novel EGFR tyrosine kinase inhibitor with...
3.
Catchpole I, Germaschewski V, Hoh Kam J, Lundh von Leithner P, Ford S, Gough G, et al.
PLoS One
. 2013 Jun;
8(6):e65518.
PMID: 23799019
Age-related macular degeneration (AMD) is a leading cause of legal blindness in the Western world. There are effective treatments for the vascular complications of neo-vascular AMD, but no effective therapies...
4.
Kurrasch R, Brown J, Chu M, Craigen J, Overend P, Patel B, et al.
J Rheumatol
. 2013 Jun;
40(7):1089-96.
PMID: 23729801
Objective: To investigate the safety and tolerability of a single subcutaneous (SC) dose of ofatumumab, a fully human anti-CD20 monoclonal antibody, in patients with rheumatoid arthritis (RA) taking background methotrexate...
5.
Murphy N, Grimsditch D, Vidgeon-Hart M, Groot P, Overend P, Benson G, et al.
Dis Markers
. 2006 Jan;
21(4):181-90.
PMID: 16403953
Dietary antioxidants are reported to suppress cellular expression of chemokines and adhesion molecules that recruit monocytes to the artery wall during atherosclerosis. In the present study we measured the effect...
6.
Hatcher P, Brown V, Tait D, Bate S, Overend P, Hagan J, et al.
Psychopharmacology (Berl)
. 2005 Apr;
181(2):253-9.
PMID: 15846482
Rationale And Objective: Performance on the Wisconsin Card Sorting Test (WCST), which requires patients to 'shift attention' between stimulus dimensions (sorting categories), is impaired in diseases such as schizophrenia. The...
7.
Hegyi L, Hockings P, Benson M, Busza A, Overend P, Grimsditch D, et al.
Pathol Oncol Res
. 2004 Sep;
10(3):159-65.
PMID: 15448752
High-resolution, non-invasive imaging methods are required to monitor progression and regression of atherosclerotic plaques. We investigated the use of MRI to measure changes in plaque volume and vessel remodelling during...
8.
Murphy N, Bruckdorfer K, Grimsditch D, Overend P, Vidgeon-Hart M, Groot P, et al.
Arterioscler Thromb Vasc Biol
. 2003 Jul;
23(9):1615-20.
PMID: 12842836
Objective: CC and CXC chemokines are implicated in leukocyte recruitment during development of atherosclerotic lesions, suggesting circulating levels of chemokines may be useful serum markers of atherogenesis. Serum chemokine concentrations...
9.
Murphy N, Grimsditch D, Parkin S, Vidgeon-Hart M, Overend P, Groot P, et al.
Atherosclerosis
. 2002 Jun;
163(1):69-77.
PMID: 12048123
Hyperlipidaemia may accelerate the development of atherosclerosis by enhancing the expression of chemokines by cells within the arterial wall. Chemokines of the CC subfamily are clearly implicated in atherogenesis; however,...