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Philip L McCarthy

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Articles 153
Citations 4284
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Recent Articles
1.
Banerjee R, Fritz A, Akhtar O, Freeman C, Cowan A, Shah N, et al.
Leukemia . 2025 Feb; PMID: 39994463
No abstract available.
2.
Daneshmandi S, Yan Q, Choi J, Katsuta E, MacDonald C, Goruganthu M, et al.
Cell Mol Immunol . 2024 Jun; 21(8):873-891. PMID: 38902348
Myeloid-derived suppressor cells (MDSCs) are a main driver of immunosuppression in tumors. Understanding the mechanisms that determine the development and immunosuppressive function of these cells could provide new therapeutic targets...
3.
Herr M, Balderman S, Wallace P, Zhang Y, Tario Jr J, Buxbaum N, et al.
Transplant Cell Ther . 2024 May; 30(8):808.e1-808.e13. PMID: 38801976
Haploidentical (Haplo) allogeneic HCTs (alloHCT) have been used more frequently over the last decade as survival is similar to HLA-matched related donor (MRD) alloHCTs. We aimed to identify donor and...
4.
Pasquini M, Wallace P, Logan B, Kaur M, Tario J, Howard A, et al.
J Clin Oncol . 2024 May; 42(23):2757-2768. PMID: 38701390
Purpose: Prognostic Immunophenotyping in Myeloma Response (PRIMeR) is an ancillary study of minimal residual disease (MRD) assessment for multiple myeloma by next-generation multiparameter flow cytometry (MFC). Patients were enrolled on...
5.
Daneshmandi S, Choi J, Yan Q, MacDonald C, Pandey M, Goruganthu M, et al.
Nat Commun . 2024 Mar; 15(1):2803. PMID: 38555305
Myeloid derived suppressor cells (MDSCs) are key regulators of immune responses and correlate with poor outcomes in hematologic malignancies. Here, we identify that MDSC mitochondrial fitness controls the efficacy of...
6.
McCarthy P, Attwood K, Liu X, Chen G, Minderman H, Alousi A, et al.
Bone Marrow Transplant . 2023 Dec; 59(3):334-343. PMID: 38110620
Identifying plasma biomarkers early after allo-HCT may become crucial to prevent and treat severe aGvHD. We utilized samples from 203 allo-HCT patients selected from the Blood & Marrow Transplant Clinical...
7.
Jadi O, Tang H, Olsen K, Vensko S, Zhu Q, Wang Y, et al.
Am J Hematol . 2023 Apr; 98(6):940-950. PMID: 37052167
The role of minor histocompatibility antigens (mHAs) in mediating graft versus leukemia and graft versus host disease (GvHD) following allogeneic hematopoietic cell transplantation (alloHCT) is recognized but not well-characterized. By...
8.
Mohammadpour H, Tsuji T, MacDonald C, Sarow J, Rosenheck H, Daneshmandi S, et al.
Cell Rep . 2023 Mar; 42(3):112250. PMID: 36924493
Abundant donor cytotoxic T cells that attack normal host organs remain a major problem for patients receiving allogeneic hematopoietic cell transplantation (allo-HCT). Despite an increase in our knowledge of the...
9.
Olsen K, Jadi O, Dexheimer S, Bortone D, Vensko S, Bennett S, et al.
Blood Adv . 2022 Dec; 7(9):1635-1649. PMID: 36477467
T-cell responses to minor histocompatibility antigens (mHAs) mediate graft-versus-leukemia (GVL) effects and graft-versus-host disease (GVHD) in allogeneic hematopoietic cell transplantation. Therapies that boost T-cell responses improve allogeneic hematopoietic cell transplant...
10.
Elshoury A, Maguire O, Conway A, Tario J, Soh K, Ross M, et al.
Transplant Cell Ther . 2022 Nov; 29(2):112.e1-112.e9. PMID: 36436782
Hypoxic conditions preserve the multipotency and self-renewing capacity of murine bone marrow and human cord blood stem cells. Blood samples stored in sealed blood gas tubes become hypoxic as leukocytes...