Philip Kirschner
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Explore the profile of Philip Kirschner including associated specialties, affiliations and a list of published articles.
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11
Citations
66
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Recent Articles
1.
Eberhard D, Balkenhol S, Koster A, Follert P, Upschulte E, Ostermann P, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(6):734-753.
PMID: 39196233
Prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease, increases worldwide and associates with type 2 diabetes and other cardiometabolic diseases. Here we demonstrate...
2.
Pfeffer T, Krug S, Kracke T, Schurfeld R, Colbatzky F, Kirschner P, et al.
Acta Physiol (Oxf)
. 2024 Mar;
240(4):e14126.
PMID: 38517248
Aim: Although of potential biomedical relevance, dipeptide metabolism has hardly been studied. We found the dipeptidase carnosinase-2 (CN2) to be abundant in human proximal tubules, which regulate water and solute...
3.
Grosse-Segerath L, Follert P, Behnke K, Ettich J, Buschmann T, Kirschner P, et al.
Nat Commun
. 2024 Feb;
15(1):1076.
PMID: 38316785
Recently, we have shown that after partial hepatectomy (PHx), an increased hepatic blood flow initiates liver growth in mice by vasodilation and mechanically-triggered release of angiocrine signals. Here, we use...
4.
Pfeffer T, Wetzel C, Kirschner P, Bartosova M, Poth T, Schwab C, et al.
Antioxidants (Basel)
. 2023 Jun;
12(6).
PMID: 37372000
Carnosine and anserine supplementation markedLy reduce diabetic nephropathy in rodents. The mode of nephroprotective action of both dipeptides in diabetes, via local protection or improved systemic glucose homeostasis, is uncertain....
5.
Pelligra A, Mrugala J, Griess K, Kirschner P, Nortmann O, Bartosinska B, et al.
Cell Rep
. 2023 Jun;
42(7):112703.
PMID: 37352100
No abstract available.
6.
Pelligra A, Mrugala J, Griess K, Kirschner P, Nortmann O, Bartosinska B, et al.
Cell Rep
. 2023 Jun;
42(6):112615.
PMID: 37294632
Type 2 diabetes is characterized by insulin hypersecretion followed by reduced glucose-stimulated insulin secretion (GSIS). Here we show that acute stimulation of pancreatic islets with the insulin secretagogue dextrorphan (DXO)...
7.
Levitsky Y, Pegouske D, Hammer S, Frantz N, Fisher K, Muchnik A, et al.
RSC Adv
. 2020 Mar;
9(57):33257-33267.
PMID: 32123561
Oxygen consumption is a key metric of metabolism in aerobic organisms. Current respirometric methods led to seminal discoveries despite limitations such as high sample demand, exchange with atmospheric O, and...
8.
Schwenkenbecher P, Neyazi A, Donnerstag F, Ringshausen F, Jacobs R, Stoll M, et al.
Front Immunol
. 2018 Jun;
9:1258.
PMID: 29915596
Chronic granulomatous disease (CGD) is a rare genetic immunodeficiency, which is characterized by recurrent severe bacterial and fungal infections caused by a defect in phagocytic cells due to loss of...
9.
Kumpers P, Tiede A, Kirschner P, Girke J, Ganser A, Peest D
J Med Microbiol
. 2008 Feb;
57(Pt 3):384-387.
PMID: 18287305
In addition to Legionella pneumophila, about 20 Legionella species have been documented as human pathogens. The majority of infections by non-pneumophila Legionella species occur in immunocompromised and splenectomized patients. Here,...
10.
Kola A, Kirschner P, Gohrbandt B, Chaberny I, Mattner F, Struber M, et al.
Scand J Infect Dis
. 2007 Apr;
39(5):463-5.
PMID: 17464873
We report an infection with a linezolid-resistant S. aureus in a patient with a left ventricular assist system. Linezolid should be used with caution when invasive devices or foreign materials...