Philip J Lucas
Overview
Explore the profile of Philip J Lucas including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
1292
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Sugita S, Ng T, Lucas P, Gress R, Wayne Streilein J
J Immunol
. 2005 Dec;
176(1):118-27.
PMID: 16365402
Ocular pigment epithelia contribute to immune privilege by suppressing T cell activation and converting T cells into regulatory T regulatory cells (Tregs) that inhibit bystander T cell activation. Iris pigment...
12.
El-Asady R, Yuan R, Liu K, Wang D, Gress R, Lucas P, et al.
J Exp Med
. 2005 May;
201(10):1647-57.
PMID: 15897278
Destruction of the host intestinal epithelium by donor effector T cell populations is a hallmark of graft-versus-host disease (GVHD), but the underlying mechanisms remain obscure. We demonstrate that CD8(+) T...
13.
Zamisch M, Moore-Scott B, Su D, Lucas P, Manley N, Richie E
J Immunol
. 2004 Dec;
174(1):60-7.
PMID: 15611228
Epithelial cells in the thymus produce IL-7, an essential cytokine that promotes the survival, differentiation, and proliferation of thymocytes. We identified IL-7-expressing thymic epithelial cells (TECs) throughout ontogeny and in...
14.
Lucas P, McNeil N, Hilgenfeld E, Choudhury B, Kim S, Eckhaus M, et al.
Cancer Res
. 2004 Sep;
64(18):6524-9.
PMID: 15374963
Tumorigenesis in rodents, as well as in humans, has been shown to be a multistep process, with each step reflecting an altered gene product or gene regulatory process leading to...
15.
Munitic I, Williams J, Yang Y, Dong B, Lucas P, El Kassar N, et al.
Blood
. 2004 Aug;
104(13):4165-72.
PMID: 15328149
Interleukin-7 receptor (IL-7R) levels are tightly controlled during ontogeny: high on double-negative (DN) cells, absent on double-positive (DP) cells, and high once again on thymocytes undergoing positive selection. To determine...
16.
Taylor P, Panoskaltsis-Mortari A, Swedin J, Lucas P, Gress R, Levine B, et al.
Blood
. 2004 Aug;
104(12):3804-12.
PMID: 15292057
Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after bone marrow transplantation (BMT). CD4(+)CD25(+) immune regulatory T cells (Tregs), long recognized for their critical role in induction...
17.
El Kassar N, Lucas P, Klug D, Zamisch M, Merchant M, Bare C, et al.
Blood
. 2004 May;
104(5):1419-27.
PMID: 15155461
To study interleukin-7 (IL-7) in early thymocyte development, we generated mice transgenic (Tg) for the IL-7 gene under control of the lck proximal promoter. Founder line TgA, with the lowest...
18.
Chu Y, Memon S, Sharrow S, Hakim F, Eckhaus M, Lucas P, et al.
Blood
. 2004 May;
104(4):1110-9.
PMID: 15130942
Interleukin 7 (IL-7) is critical in maintaining thymic-dependent and thymic-independent pathways of T-cell homeostasis. T-cell receptor (TCR) rearrangement excision circles (TRECs) have been used as markers for recent thymic emigrants...
19.
Wang D, Yuan R, Feng Y, El-Asady R, Farber D, Gress R, et al.
J Immunol
. 2003 Dec;
172(1):214-21.
PMID: 14688328
CD103 is an integrin with specificity for the epithelial cell-specific ligand, E-cadherin. Recent studies indicate that CD103 expression endows peripheral CD8 cells with a unique capacity to access the epithelial...