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Philip Britz-McKibbin

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Articles 113
Citations 1318
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Recent Articles
1.
Helmeczi E, Pandya H, OHearn K, McNally D, Britz-McKibbin P
J Steroid Biochem Mol Biol . 2025 Mar; 250:106720. PMID: 40064426
Vitamin D deficiency (VDD) is prevalent globally and in pediatric intensive care units, where it represents a modifiable risk factor that may impact patient recovery during hospitalization. Herein, we performed...
2.
Stanciu A, Gillespie C, Britz-McKibbin P
Annu Rev Anal Chem (Palo Alto Calif) . 2025 Feb; PMID: 39929542
Exposomics refers to the comprehensive analysis of environmental exposures over the lifespan and assessment of their biological effects on human health. This new frontier in environmental research promises new insights...
3.
Padilha M, Keller V, Normando P, Schincaglia R, Freitas-Costa N, Freire S, et al.
Elife . 2025 Jan; 14. PMID: 39812094
Background: The role of circulating metabolites on child development is understudied. We investigated associations between children's serum metabolome and early childhood development (ECD). Methods: Untargeted metabolomics was performed on serum...
4.
Helmeczi E, Kroezen Z, Shanmuganathan M, Stanciu A, Martinez V, Kurysko N, et al.
Anal Chem . 2024 Dec; 97(1):175-184. PMID: 39729551
Mass spectrometry (MS)-based metabolomics often rely on separation techniques when analyzing complex biological specimens to improve method resolution, metabolome coverage, quantitative performance, and/or unknown identification. However, low sample throughput and...
5.
Kamal M, Shanmuganathan M, Kroezen Z, Joanisse S, Britz-McKibbin P, Parise G
Am J Physiol Cell Physiol . 2024 Dec; 328(2):C440-C451. PMID: 39726265
Cellular senescence has been implicated in the aging-related dysfunction of satellite cells, the resident muscle stem cell population primarily responsible for the repair of muscle fibers. Despite being in a...
6.
Baskaran K, Moshkovich M, Hart L, Shah N, Chowdhury F, Shanmuganathan M, et al.
Biomarkers . 2024 Dec; 30(1):104-113. PMID: 39642943
Introduction: Urine metabolomics offers a non-invasive approach to diagnose and manage inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), by identifying distinct metabolic signatures. Objectives: This...
7.
OHearn K, Menon K, Albrecht L, Amrein K, Britz-McKibbin P, Cayouette F, et al.
Trials . 2024 Sep; 25(1):619. PMID: 39300483
Background: The rate of vitamin D deficiency (VDD) in critically ill children worldwide has been estimated at 50%. These children are at risk of multiple organ dysfunction, chronic morbidity, and...
8.
Azab S, Hum R, Britz-McKibbin P
Anal Sci Adv . 2024 May; 1(3):173-182. PMID: 38716130
Perfluoroalkyl substances (PFASs) are a major contaminant class due to their ubiquitous prevalence, persistence, and putative endocrine disrupting activity that may contribute to chronic disease risk notably with exposures early...
9.
Barker-Tejeda T, Zubeldia-Varela E, Macias-Camero A, Alonso L, Martin-Antoniano I, Rey-Stolle M, et al.
Nat Commun . 2024 Apr; 15(1):3004. PMID: 38589361
The human gut microbiome establishes and matures during infancy, and dysregulation at this stage may lead to pathologies later in life. We conducted a multi-omics study comprising three generations of...
10.
Ly R, Torres L, Ly N, Britz-McKibbin P
Anal Chem . 2023 Nov; 95(48):17513-17524. PMID: 37991882
Orthogonal separation techniques coupled to high-resolution mass spectrometry are required for characterizing the human lipidome, given its inherent chemical and structural complexity. However, electrophoretic separations remain largely unrecognized in contemporary...