Phalguni Gupta
Overview
Explore the profile of Phalguni Gupta including associated specialties, affiliations and a list of published articles.
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80
Citations
1307
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Recent Articles
1.
Sanyal A, Rangachar V, Gupta P
Bio Protoc
. 2019 Aug;
9(10).
PMID: 31428662
The latent HIV-1 viral reservoir in resting CD4 (rCD4) T cells represents a major barrier to an HIV-1 cure. There is an ongoing effort to identify therapeutic approaches that will...
2.
Kristoff J, Palma M, Garcia-Bates T, Shen C, Sluis-Cremer N, Gupta P, et al.
EBioMedicine
. 2019 Apr;
43:295-306.
PMID: 30952614
Background: Despite the success of antiretroviral therapy (ART), latent HIV-1 continues to persist in a long-lived population of resting memory CD4 T cells within those who are infected. Finding a...
3.
Sanyal A, Shen C, Ding M, Reinhart T, Chen Y, Sankapal S, et al.
Am J Reprod Immunol
. 2019 Mar;
81(6):e13111.
PMID: 30903720
Problem: Neisseria gonorrhoeae (NG) infection has been shown to increase sexual transmission of HIV-1. However, the mechanism of NG-induced enhanced HIV-1 transmission is unknown. Methods: (a) The cervical tissues were...
4.
Vargas B, Giacobbi N, Sanyal A, Venkatachari N, Han F, Gupta P, et al.
Antimicrob Agents Chemother
. 2018 Nov;
63(2).
PMID: 30455231
Signaling pathways play a key role in HIV-1 latency. In this study, we used the 24ST1NLESG cell line of HIV-1 latency to screen a library of structurally diverse, medicinally active,...
5.
Samal J, Kelly S, Na-Shatal A, Elhakiem A, Das A, Ding M, et al.
JCI Insight
. 2018 Sep;
3(18).
PMID: 30232273
A major pathogenic feature associated with HIV infection is lymphoid fibrosis, which persists during antiretroviral therapy (ART). Lymphoid tissues play critical roles in the generation of antigen-specific immune response, and...
6.
Gong T, Zhang W, Parniak M, Graebing P, Moncla B, Gupta P, et al.
J Pharm Innov
. 2017 Oct;
12(2):142-154.
PMID: 28983328
Purpose: 5-chloro-3-[phenylsulfonyl] indole-2-carboxamide (CSIC) is a highly potent non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 which has been shown to have a more desirable resistance profile than other NNRTIs in...
7.
Gupta P, Sanyal A, Mailliard R
Expert Rev Mol Diagn
. 2017 Sep;
17(12):1033-1035.
PMID: 28937839
No abstract available.
8.
Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4 T cells
Sanyal A, Mailliard R, Rinaldo C, Ratner D, Ding M, Chen Y, et al.
Nat Med
. 2017 May;
23(7):885-889.
PMID: 28553933
Although antiretroviral therapy can suppress HIV-1 infection to undetectable levels of plasma viremia, integrated latent HIV-1 genomes that encode replication-competent virus persist in resting CD4 T cells. This latent HIV-1...
9.
Welch J, Madison M, Margolick J, Galvin S, Gupta P, Martinez-Maza O, et al.
Sci Rep
. 2017 Mar;
7:45034.
PMID: 28338013
Exosomes are important vehicles of intercellular communication that shape host responses to physiologic, tumorigenic, and pathogenic conditions. The composition and function of exosomes are dynamic and depends on the state...
10.
Chen Y, Shen C, Guha D, Ding M, Kulich S, Ashimkhanova A, et al.
BMC Infect Dis
. 2016 Nov;
16(1):693.
PMID: 27875997
Background: Infection with human immunodeficiency virus (HIV) influences the outcome and natural disease progression of hepatitis C virus (HCV) infection. While the majority of HCV mono-infected and HCV/HIV co-infected subjects...