Petra Malova
Overview
Explore the profile of Petra Malova including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
18
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Recent Articles
1.
Peck S, Cooke H, Cicchillo R, Malova P, Hammerschmidt F, Nair S, et al.
Biochemistry
. 2011 Jun;
50(30):6598-605.
PMID: 21711001
HEPD belongs to the superfamily of 2-His-1-carboxylate non-heme iron-dependent dioxygenases. It converts 2-hydroxyethylphosphonate (2-HEP) to hydroxymethylphosphonate (HMP) and formate. Previously postulated mechanisms for the reaction catalyzed by HEPD cannot explain...
2.
Whitteck J, Malova P, Peck S, Cicchillo R, Hammerschmidt F, van der Donk W
J Am Chem Soc
. 2011 Mar;
133(12):4236-9.
PMID: 21381767
Stereochemical investigations have shown that the conversion of 2-hydroxyethylphosphonate to hydroxymethylphosphonate by the enzyme HEPD involves removal of the pro-S hydrogen at C2 and, surprisingly, the loss of stereochemical information...