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Petra Kosutova

Explore the profile of Petra Kosutova including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 296
Followers 0
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Recent Articles
1.
Mikolka P, Kosutova P, Kolomaznik M, Nemcova N, Hanusrichterova J, Curstedt T, et al.
Lung . 2024 Apr; 202(3):299-315. PMID: 38684519
Purpose: Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory failure in adults. In ARDS extensive inflammation and leakage of fluid into the alveoli lead to dysregulation...
2.
Kolomaznik M, Hanusrichterova J, Mikolka P, Kosutova P, Vatecha M, Zila I, et al.
Respir Physiol Neurobiol . 2023 Aug; 316:104138. PMID: 37579929
Accumulation of reactive oxygen species during hyperoxia together with secondary bacteria-induced inflammation leads to lung damage in ventilated critically ill patients. Antioxidant N-acetylcysteine (NAC) in combination with surfactant may improve...
3.
Mikolka P, Kronqvist N, Haegerstrand-Bjorkman M, Jaudzems K, Kosutova P, Kolomaznik M, et al.
Transl Res . 2023 Jul; 262:60-74. PMID: 37499744
Respiratory distress syndrome (RDS) in premature infants is caused by insufficient amounts of endogenous lung surfactant and is efficiently treated with replacement therapy using animal-derived surfactant preparations. On the other...
4.
Kosutova P, Mikolka P, Mokra D, Calkovska A
J Inflamm (Lond) . 2023 Mar; 20(1):10. PMID: 36927675
Acute respiratory distress syndrome (ARDS) is a common complication of critical illness characterized by lung inflammation, epithelial and endothelial dysfunction, alveolar-capillary leakage, and worsening respiratory failure. The present study aimed...
5.
Kosutova P, Nemcova N, Kolomaznik M, Mokra D, Calkovska A, Mikolka P
Antioxidants (Basel) . 2023 Jan; 12(1). PMID: 36670899
Aspirated meconium into a newborn's airways induces the transcription of pro-oxidative mediators that cooperate in the pathogenesis of inflammatory changes and may negatively affect the commonly used exogenous surfactant therapy....
6.
Kosutova P, Kolomaznik M, Calkovska A, Mokra D, Mikolka P
Pharmaceutics . 2021 Dec; 13(12). PMID: 34959373
Acute respiratory distress syndrome (ARDS) is a common complication of critical illness and remains a major source of morbidity and mortality in the intensive care unit (ICU). ARDS is characterised...
7.
Kolomaznik M, Mikolka P, Hanusrichterova J, Kosutova P, Matasova Jr K, Mokra D, et al.
Biomedicines . 2021 Dec; 9(12). PMID: 34944701
Treatment of acute respiratory distress syndrome (ARDS) is challenging due to its multifactorial aetiology. The benefit of antioxidant therapy was not consistently demonstrated by previous studies. We evaluated the effect...
8.
Kolomaznik M, Kopincova J, Nova Z, Topercerova J, Zila I, Mikolka P, et al.
Molecules . 2020 Sep; 25(19). PMID: 32977392
The study aimed to prove the hypothesis that exogenous surfactant and an antibiotic polymyxin B (PxB) can more effectively reduce lipopolysaccharide (LPS)-induced acute lung injury (ALI) than surfactant treatment alone,...
9.
Kosutova P, Mikolka P, Balentova S, Adamkov M, Calkovska A, Mokra D
Int J Mol Sci . 2020 May; 21(9). PMID: 32403267
This study aimed to investigate whether a selective phosphodiesterase-3 (PDE3) inhibitor olprinone can positively influence the inflammation, apoptosis, and respiratory parameters in animals with acute respiratory distress syndrome (ARDS) model...
10.
Kertys M, Grendar M, Kosutova P, Mokra D, Mokry J
Biochim Biophys Acta Mol Basis Dis . 2019 Nov; 1866(1):165572. PMID: 31672552
Bronchial asthma is one of the most common, chronic respiratory diseases, characterized by reversible airway obstruction, eosinophil and Th2 infiltration, airway hyperresponsiveness and airway remodelling; with many cells and mediators...