Maros Kolomaznik
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Explore the profile of Maros Kolomaznik including associated specialties, affiliations and a list of published articles.
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11
Citations
34
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Recent Articles
1.
Mikolka P, Kosutova P, Kolomaznik M, Nemcova N, Hanusrichterova J, Curstedt T, et al.
Lung
. 2024 Apr;
202(3):299-315.
PMID: 38684519
Purpose: Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory failure in adults. In ARDS extensive inflammation and leakage of fluid into the alveoli lead to dysregulation...
2.
Kolomaznik M, Hanusrichterova J, Mikolka P, Kosutova P, Vatecha M, Zila I, et al.
Respir Physiol Neurobiol
. 2023 Aug;
316:104138.
PMID: 37579929
Accumulation of reactive oxygen species during hyperoxia together with secondary bacteria-induced inflammation leads to lung damage in ventilated critically ill patients. Antioxidant N-acetylcysteine (NAC) in combination with surfactant may improve...
3.
Mikolka P, Kronqvist N, Haegerstrand-Bjorkman M, Jaudzems K, Kosutova P, Kolomaznik M, et al.
Transl Res
. 2023 Jul;
262:60-74.
PMID: 37499744
Respiratory distress syndrome (RDS) in premature infants is caused by insufficient amounts of endogenous lung surfactant and is efficiently treated with replacement therapy using animal-derived surfactant preparations. On the other...
4.
Kosutova P, Nemcova N, Kolomaznik M, Mokra D, Calkovska A, Mikolka P
Antioxidants (Basel)
. 2023 Jan;
12(1).
PMID: 36670899
Aspirated meconium into a newborn's airways induces the transcription of pro-oxidative mediators that cooperate in the pathogenesis of inflammatory changes and may negatively affect the commonly used exogenous surfactant therapy....
5.
Kosutova P, Kolomaznik M, Calkovska A, Mokra D, Mikolka P
Pharmaceutics
. 2021 Dec;
13(12).
PMID: 34959373
Acute respiratory distress syndrome (ARDS) is a common complication of critical illness and remains a major source of morbidity and mortality in the intensive care unit (ICU). ARDS is characterised...
6.
Kolomaznik M, Mikolka P, Hanusrichterova J, Kosutova P, Matasova Jr K, Mokra D, et al.
Biomedicines
. 2021 Dec;
9(12).
PMID: 34944701
Treatment of acute respiratory distress syndrome (ARDS) is challenging due to its multifactorial aetiology. The benefit of antioxidant therapy was not consistently demonstrated by previous studies. We evaluated the effect...
7.
Kolomaznik M, Kopincova J, Nova Z, Topercerova J, Zila I, Mikolka P, et al.
Molecules
. 2020 Sep;
25(19).
PMID: 32977392
The study aimed to prove the hypothesis that exogenous surfactant and an antibiotic polymyxin B (PxB) can more effectively reduce lipopolysaccharide (LPS)-induced acute lung injury (ALI) than surfactant treatment alone,...
8.
Kopincova J, Kolomaznik M, Mikolka P, Kosutova P, Topercerova J, Matasova Jr K, et al.
Molecules
. 2019 Mar;
24(5).
PMID: 30841517
This study aimed to evaluate the molecular background of -acetylcysteine (NAC) and recombinant human superoxide dismutase (rhSOD) antioxidant action when combined with exogenous surfactant in the treatment of meconium aspiration...
9.
Kolomaznik M, Liskayova G, Kanjakova N, Hubcik L, Uhrikova D, Calkovska A
Int J Mol Sci
. 2018 Jul;
19(7).
PMID: 29976869
After inhalation, lipopolysaccharide (LPS) molecules interfere with a pulmonary surfactant, a unique mixture of phospholipids (PLs) and specific proteins that decreases surface tension at the air⁻liquid interphase. We evaluated the...
10.
Kopincova J, Mikolka P, Kolomaznik M, Kosutova P, Calkovska A, Mokra D
Life Sci
. 2018 Apr;
203:121-128.
PMID: 29684443
Aims: Combination of exogenous surfactant with antioxidant enzyme recombinant human superoxide dismutase (rhSOD) was tested in the treatment of experimental meconium aspiration syndrome as oxidative processes play key role in...