Peter W Piper
Overview
Explore the profile of Peter W Piper including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
2851
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0
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Recent Articles
1.
Millson S, Truman A, Piper P
Cell Stress Chaperones
. 2022 Apr;
27(3):295-304.
PMID: 35420390
In yeast, the Slt2(Mpk1) stress-activated protein kinase directs the activation of two transcription factors, Rlm1 and Swi4/Swi6, in response to cell wall stress. Rlm1 is activated through a phosphorylation by...
2.
Piper J, Piper P
Compr Rev Food Sci Food Saf
. 2020 Dec;
16(5):868-880.
PMID: 33371618
Sodium benzoate and potassium sorbate are extremely useful agents for food and beverage preservation, yet concerns remain over their complete safety. Benzoate can react with the ascorbic acid in drinks...
3.
Escalante S, Brightmore J, Piper P, Millson S
Cell Stress Chaperones
. 2017 Dec;
23(4):609-615.
PMID: 29288355
A dedicated UNC45, Cro1, She4 (UCS) domain-containing protein assists in the Hsp90-mediated folding of the myosin head. Only weak sequence conservation exists between the single UCS protein of simple eukaryotes...
4.
Gomez-Escalante S, Piper P, Millson S
Cell Stress Chaperones
. 2016 Nov;
22(1):135-141.
PMID: 27888470
Folding of the myosin head often requires the joint actions of Hsp90 and a dedicated UNC45, Cro1, She4 (UCS) domain-containing cochaperone protein. Relatively weak sequence conservation exists between the single...
5.
Piper P, Millson S
Pharmaceuticals (Basel)
. 2016 Oct;
4(11):1400-1422.
PMID: 27721330
The molecular chaperone Hsp90 holds great promise as a cancer drug target, despite some of the initial clinical trials of Hsp90 inhibitor drugs having not lived up to expectation. Effective...
6.
Millson S, Piper P
Oncotarget
. 2014 Jun;
5(13):5054-64.
PMID: 24970820
Unlabelled: In human cells TORC1 mTOR (target of rapamycin) protein kinase complex renders heat shock transcription factor 1 (Hsf1) competent for stress activation. In such cells, as well as in...
7.
Millson S, van Oosten-Hawle P, Alkuriji M, Truman A, Siderius M, Piper P
Cell Stress Chaperones
. 2014 Jan;
19(5):695-703.
PMID: 24452458
In most eukaryotes, Cdc37 is an essential chaperone, transiently associating with newly synthesised protein kinases in order to promote their stabilisation and activation. To determine whether the yeast Cdc37 participates...
8.
Piper P, Millson S
Open Biol
. 2012 Dec;
2(12):120138.
PMID: 23271830
Heat shock protein 90 (Hsp90) is a promising cancer drug target as a molecular chaperone critical for stabilization and activation of several of the oncoproteins that drive cancer progression. Its...
9.
Mollapour M, Piper P
Yeast
. 2011 Nov;
29(1):39-44.
PMID: 22113732
Saccharomyces cerevisiae acquires its resistance to carboxylate weak organic acids by inducing a plasma membrane ABC transporter, Pdr12. These acids activate a Zn(II)2Cys6 zinc-finger transcription factor, War1, which in turn...
10.
Piper P
Subcell Biochem
. 2011 Nov;
57:145-59.
PMID: 22094421
When investigating aging it is important to focus on the factors that are needed to attain, and which can be manipulated to extend, the longest lifespans. This has long been...