Peter W Andrew
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Explore the profile of Peter W Andrew including associated specialties, affiliations and a list of published articles.
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119
Citations
4386
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Recent Articles
11.
Shlla B, Gazioglu O, Shafeeq S, Manzoor I, Kuipers O, Ulijasz A, et al.
Mol Microbiol
. 2021 Jul;
116(3):996-1008.
PMID: 34328238
Rggs are a group of transcriptional regulators with diverse roles in metabolism and virulence. Here, we present work on the Rgg1518/SHP1518 quorum sensing system of Streptococcus pneumoniae. The activity of...
12.
Fernandes V, Ercoli G, Benard A, Brandl C, Fahnenstiel H, Muller-Winkler J, et al.
PLoS Pathog
. 2020 Apr;
16(4):e1008464.
PMID: 32324805
Streptococcus pneumoniae is a major human pathogen, causing pneumonia and sepsis. Genetic components strongly influence host responses to pneumococcal infections, but the responsible loci are unknown. We have previously identified...
13.
Faraj B, Collard L, Cliffe R, Blount L, Lonnen R, Wallis R, et al.
Sci Rep
. 2020 Mar;
10(1):4585.
PMID: 32165654
Oligomers of pneumolysin form transmembrane channels in cholesterol-containing lipid bilayers. The mechanism of pore formation involves a multistage process in which the protein, at first, assembles into a ring-shaped complex...
14.
Motib A, Al-Bayati F, Manzoor I, Shafeeq S, Kadam A, Kuipers O, et al.
Front Cell Infect Microbiol
. 2019 Oct;
9:326.
PMID: 31572692
is able to cause deadly diseases by infecting different tissues, each with distinct environmental and nutritional compositions. We hypothesize that the adaptive capabilities of the microbe is an important facet...
15.
Haleem K, Ali Y, Yesilkaya H, Kohler T, Hammerschmidt S, Andrew P, et al.
Infect Immun
. 2018 Oct;
87(1).
PMID: 30323030
Complement is a critical component of antimicrobial immunity. Various complement regulatory proteins prevent host cells from being attacked. Many pathogens have acquired the ability to sequester complement regulators from host...
16.
Zhi X, Abdullah I, Gazioglu O, Manzoor I, Shafeeq S, Kuipers O, et al.
Sci Rep
. 2018 Apr;
8(1):6369.
PMID: 29686372
Microbes communicate with each other by using quorum sensing (QS) systems and modulate their collective 'behavior' for in-host colonization and virulence, biofilm formation, and environmental adaptation. The recent increase in...
17.
Ercoli G, Fernandes V, Chung W, Wanford J, Thomson S, Bayliss C, et al.
Nat Microbiol
. 2018 Apr;
3(5):600-610.
PMID: 29662129
Bacterial septicaemia is a major cause of mortality, but its pathogenesis remains poorly understood. In experimental pneumococcal murine intravenous infection, an initial reduction of bacteria in the blood is followed...
18.
Purves J, Thomas J, Riboldi G, Zapotoczna M, Tarrant E, Andrew P, et al.
Environ Microbiol
. 2018 Mar;
20(4):1576-1589.
PMID: 29521441
Excess copper is highly toxic and forms part of the host innate immune system's antibacterial arsenal, accumulating at sites of infection and acting within macrophages to kill engulfed pathogens. We...
19.
Motib A, Guerreiro A, Al-Bayati F, Piletska E, Manzoor I, Shafeeq S, et al.
Angew Chem Int Ed Engl
. 2017 Nov;
56(52):16555-16558.
PMID: 29140595
We describe the development, characterization, and biological testing of a new type of linear molecularly imprinted polymer (LMIP) designed to act as an anti-infective by blocking the quorum sensing (QS)...
20.
Collard L, Perez-Guaita D, Faraj B, Wood B, Wallis R, Andrew P, et al.
Sci Rep
. 2017 Aug;
7(1):8589.
PMID: 28819244
A spectroscopic technique is presented that is able to identify rapid changes in the bending modulus and fluidity of vesicle lipid bilayers on the micrometer scale, and distinguish between the...