Peter van Lent
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Explore the profile of Peter van Lent including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
406
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Recent Articles
1.
von Wulffen M, Luehrmann V, Robeck S, Russo A, Fischer-Riepe L, van den Bosch M, et al.
Cell Rep
. 2023 Aug;
42(8):113006.
PMID: 37610870
Immune-suppressive effects of myeloid-derived suppressor cells (MDSCs) are well characterized during anti-tumor immunity. The complex mechanisms promoting MDSC development and their regulatory effects during autoimmune diseases are less understood. We...
2.
Thielen N, Neefjes M, Wiegertjes R, van den Akker G, Vitters E, van Beuningen H, et al.
Int J Mol Sci
. 2021 Aug;
22(15).
PMID: 34360888
Osteoarthritis (OA) is a degenerative joint disease characterized by irreversible cartilage damage, inflammation and altered chondrocyte phenotype. Transforming growth factor-β (TGF-β) signaling via SMAD2/3 is crucial for blocking hypertrophy. The...
3.
Hafsia N, Forien M, Renaudin F, Delacour D, Reboul P, van Lent P, et al.
Int J Mol Sci
. 2020 Feb;
21(4).
PMID: 32098291
Mechanical overload and aging are the main risk factors of osteoarthritis (OA). Galectin 3 (GAL3) is important in the formation of primary cilia, organelles that are able to sense mechanical...
4.
van Caam A, Vonk M, van den Hoogen F, van Lent P, van der Kraan P
Front Immunol
. 2018 Nov;
9:2452.
PMID: 30483246
Systemic sclerosis (SSc) is a severe auto-immune disease, characterized by vasculopathy and fibrosis of connective tissues. SSc has a high morbidity and mortality and unfortunately no disease modifying therapy is...
5.
Gran S, Honold L, Fehler O, Zenker S, Eligehausen S, Kuhlmann M, et al.
Theranostics
. 2018 May;
8(9):2407-2423.
PMID: 29721088
Recruitment of leukocytes from the blood to sites of inflammation poses a promising target for new diagnostic and therapeutic approaches. We aimed to develop a novel method to non-invasively analyze...
6.
de Korte A, Aquarius R, Meijer F, van Lent P, Boogaarts H, de Vries J
Br J Neurosurg
. 2017 May;
33(3):258-260.
PMID: 28494622
We demonstrate the presence of S100A8 and S100A9 proteins in the wall and thrombosed lumen of an enlarged intracranial aneurysm after flow diverter treatment. These proteins have shown to play...
7.
Benigni G, Dimitrova P, Antonangeli F, Sanseviero E, Milanova V, Blom A, et al.
J Immunol
. 2017 Jan;
198(5):2115-2124.
PMID: 28108560
Several immune cell populations are involved in cartilage damage, bone erosion, and resorption processes during osteoarthritis. The purpose of this study was to investigate the role of NK cells in...
8.
Toupet K, Maumus M, Luz-Crawford P, Lombardo E, Lopez-Belmonte J, van Lent P, et al.
PLoS One
. 2015 Jan;
10(1):e0114962.
PMID: 25559623
Background: Application of mesenchymal stem/stromal cells (MSCs) in treating different disorders, in particular osteo-articular diseases, is currently under investigation. We have already documented the safety of administrating human adipose tissue-derived...
9.
Vogl T, Eisenblatter M, Voller T, Zenker S, Hermann S, van Lent P, et al.
Nat Commun
. 2014 Aug;
5:4593.
PMID: 25098555
Inflammation has a key role in the pathogenesis of various human diseases. The early detection, localization and monitoring of inflammation are crucial for tailoring individual therapies. However, reliable biomarkers to...
10.
Nasi S, Ea H, Chobaz V, van Lent P, Liote F, So A, et al.
Joint Bone Spine
. 2014 Apr;
81(4):320-4.
PMID: 24703622
Objectives: The aim of our study was to evaluate the role of cell-membrane expressed TLRs and the signaling molecule MyD88 in a murine model of OA induced by knee menisectomy...