Peter Usatyuk
Overview
Explore the profile of Peter Usatyuk including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
391
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0
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Recent Articles
1.
Kawada I, Hasina R, Lennon F, Bindokas V, Usatyuk P, Tan Y, et al.
Cancer Biol Ther
. 2013 Jun;
14(7):679-91.
PMID: 23792636
Cytoskeletal and focal adhesion abnormalities are observed in several types of cancer, including lung cancer. We have previously reported that paxillin (PXN) was mutated, amplified, and overexpressed in a significant...
2.
Jensen A, David S, Liao C, Dai J, Keller E, Al-Ahmadie H, et al.
Clin Cancer Res
. 2011 Mar;
17(10):3112-22.
PMID: 21364031
Purpose: Fyn is a member of the Src family of kinases that we have previously shown to be overexpressed in prostate cancer. This study defines the biological impact of Fyn...
3.
Berdyshev E, Gorshkova I, Usatyuk P, Kalari S, Zhao Y, Pyne N, et al.
PLoS One
. 2011 Feb;
6(1):e16571.
PMID: 21304987
Background: Earlier we have shown that extracellular sphingosine-1-phosphate (S1P) induces migration of human pulmonary artery endothelial cells (HPAECs) through the activation of S1P(1) receptor, PKCε, and PLD2-PKCζ-Rac1 signaling cascade. As...
4.
Berdyshev E, Gorshkova I, Usatyuk P, Zhao Y, Saatian B, Hubbard W, et al.
Cell Signal
. 2006 Mar;
18(10):1779-92.
PMID: 16529909
Sphingosine kinase 1 (SK1) is one of the two known kinases, which generates sphingosine-1-phosphate (S1P), a potent endogenous lipid mediator involved in cell survival, proliferation, and cell-cell interactions. Activation of...
5.
Kolosova I, Mirzapoiazova T, Adyshev D, Usatyuk P, Romer L, Jacobson J, et al.
Circ Res
. 2005 Jul;
97(2):115-24.
PMID: 15994434
Endothelial barrier dysfunction caused by inflammatory agonists is a frequent underlying cause of vascular leak and edema. Novel strategies to preserve barrier integrity could have profound clinical impact. Adenosine triphosphate...
6.
Birukova A, Birukov K, Adyshev D, Usatyuk P, Natarajan V, Garcia J, et al.
J Cell Physiol
. 2005 Apr;
204(3):934-47.
PMID: 15828024
Transforming growth factor-beta1 (TGF-beta1) is a cytokine critically involved in acute lung injury and endothelial cell (EC) barrier dysfunction. We have studied TGF-beta1-mediated signaling pathways and examined a role of...
7.
Birukova A, Smurova K, Birukov K, Usatyuk P, Liu F, Kaibuchi K, et al.
J Cell Physiol
. 2004 Jul;
201(1):55-70.
PMID: 15281089
Barrier dysfunction of pulmonary endothelial monolayer is associated with dramatic cytoskeletal reorganization, activation of actomyosin contractility, and gap formation. The linkage between the microtubule (MT) network and the contractile cytoskeleton...
8.
Cummings R, Parinandi N, Wang L, Usatyuk P, Natarajan V
Mol Cell Biochem
. 2002 Aug;
234-235(1-2):99-109.
PMID: 12162465
Phospholipase D (PLD), a phospholipid phosphohydrolase, catalyzes the hydrolysis of phosphatidylcholine and other membrane phospholipids to phosphatidic acid (PA) and choline. PLD, ubiquitous in mammals, is a critical enzyme in...
9.
Wang L, Cummings R, Usatyuk P, Morris A, Irani K, Natarajan V
Biochem J
. 2002 Aug;
367(Pt 3):751-60.
PMID: 12149127
Sphingosine 1-phosphate (S1P), a metabolite of sphingomyelin degradation, stimulates interleukin-8 (IL-8) secretion in human bronchial epithelial (Beas-2B) cells. The molecular mechanisms regulating S1P-mediated IL-8 secretion are yet to be completely...