Peter T Tsai
Overview
Explore the profile of Peter T Tsai including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
1414
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dentel B, Angeles-Perez L, Flores A, Lei K, Ren C, Sanchez A, et al.
Neurobiol Dis
. 2025 Jan;
205():106790.
PMID: 39765274
Loss of function in the subunits of the GTPase-activating protein (GAP) activity toward Rags-1 (GATOR1) complex, an amino-acid sensitive negative regulator of the mechanistic target of rapamycin complex 1 (mTORC1),...
2.
Gibson J, Vazquez A, Yamashiro K, Jakkamsetti V, Ren C, Lei K, et al.
Cell Rep
. 2023 Dec;
42(12):113533.
PMID: 38048226
Cerebellar dysfunction has been linked to autism spectrum disorders (ASDs). Although cerebellar pathology has been observed in individuals with fragile X syndrome (FXS) and in mouse models of the disorder,...
3.
Barone I, Gilette N, Hawks-Mayer H, Handy J, Zhang K, Chifamba F, et al.
Sci Adv
. 2023 Oct;
9(43):eadj1010.
PMID: 37878694
The time of day strongly influences adaptive behaviors like long-term memory, but the correlating synaptic and molecular mechanisms remain unclear. The circadian clock comprises a canonical transcription-translation feedback loop (TTFL)...
4.
Dentel B, Angeles-Perez L, Ren C, Jakkamsetti V, Holley A, Caballero D, et al.
iScience
. 2022 May;
25(5):104334.
PMID: 35602938
Targeted therapies for epilepsies associated with the mTORC1 signaling negative regulator GATOR1 are lacking. NPRL2 is a subunit of the GATOR1 complex and mutations in GATOR1 subunits, including , are...
5.
Gibson J, Howland C, Ren C, Howland C, Vernino A, Tsai P
J Neurosci
. 2022 Feb;
42(13):2804-2823.
PMID: 35190469
The cerebellum has been increasingly implicated in autism spectrum disorder (ASD) with many ASD-linked genes impacting both cerebellar function and development. However, the precise timing and critical periods of when...
6.
Stoodley C, Tsai P
Annu Rev Neurosci
. 2021 Jul;
44:475-493.
PMID: 34236892
Social interactions involve processes ranging from face recognition to understanding others' intentions. To guide appropriate behavior in a given context, social interactions rely on accurately predicting the outcomes of one's...
7.
Kelly E, Escamilla C, Tsai P
Neuroscience
. 2020 Nov;
462:274-287.
PMID: 33253824
Autism spectrum disorders (ASD) are highly prevalent neurodevelopmental disorders; however, the neurobiological mechanisms underlying disordered behavior in ASD remain poorly understood. Notably, individuals with ASD have demonstrated difficulties generating implicitly...
8.
Kelly E, Meng F, Fujita H, Morgado F, Kazemi Y, Rice L, et al.
Nat Neurosci
. 2020 Jul;
23(9):1102-1110.
PMID: 32661395
Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs); however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain unknown. In this study, we demonstrated functional connectivity between the...
9.
Dentel B, Escamilla C, Tsai P
Neuron
. 2020 Jan;
104(6):1032-1033.
PMID: 31951535
Dysregulated mTOR contributes to neurodevelopmental dysfunction. A new study (Chen et al., 2019) demonstrates that suppression of mTORC2, not mTORC1, ameliorates survival, seizures, and abnormal behaviors in a Pten mutant...
10.
Tsai P, Rudolph S, Guo C, Ellegood J, Gibson J, Schaeffer S, et al.
Cell Rep
. 2018 Oct;
25(2):357-367.e4.
PMID: 30304677
Despite a prevalence exceeding 1%, mechanisms underlying autism spectrum disorders (ASDs) are poorly understood, and targeted therapies and guiding parameters are urgently needed. We recently demonstrated that cerebellar dysfunction is...