Chongyu Ren
Overview
Explore the profile of Chongyu Ren including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
444
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0
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Recent Articles
1.
Dentel B, Angeles-Perez L, Flores A, Lei K, Ren C, Sanchez A, et al.
Neurobiol Dis
. 2025 Jan;
205():106790.
PMID: 39765274
Loss of function in the subunits of the GTPase-activating protein (GAP) activity toward Rags-1 (GATOR1) complex, an amino-acid sensitive negative regulator of the mechanistic target of rapamycin complex 1 (mTORC1),...
2.
Gibson J, Vazquez A, Yamashiro K, Jakkamsetti V, Ren C, Lei K, et al.
Cell Rep
. 2023 Dec;
42(12):113533.
PMID: 38048226
Cerebellar dysfunction has been linked to autism spectrum disorders (ASDs). Although cerebellar pathology has been observed in individuals with fragile X syndrome (FXS) and in mouse models of the disorder,...
3.
Dentel B, Angeles-Perez L, Ren C, Jakkamsetti V, Holley A, Caballero D, et al.
iScience
. 2022 May;
25(5):104334.
PMID: 35602938
Targeted therapies for epilepsies associated with the mTORC1 signaling negative regulator GATOR1 are lacking. NPRL2 is a subunit of the GATOR1 complex and mutations in GATOR1 subunits, including , are...
4.
Gibson J, Howland C, Ren C, Howland C, Vernino A, Tsai P
J Neurosci
. 2022 Feb;
42(13):2804-2823.
PMID: 35190469
The cerebellum has been increasingly implicated in autism spectrum disorder (ASD) with many ASD-linked genes impacting both cerebellar function and development. However, the precise timing and critical periods of when...
5.
Kelly E, Meng F, Fujita H, Morgado F, Kazemi Y, Rice L, et al.
Nat Neurosci
. 2020 Jul;
23(9):1102-1110.
PMID: 32661395
Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs); however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain unknown. In this study, we demonstrated functional connectivity between the...
6.
Jin H, Zhang Y, Liu D, Wang S, Ding Q, Rastogi P, et al.
Am J Pathol
. 2019 Nov;
190(1):176-189.
PMID: 31676329
Nephronophthisis (NPHP), the leading genetic cause of end-stage renal failure in children and young adults, is a group of autosomal recessive diseases characterized by kidney-cyst degeneration and fibrosis for which...
7.
Li Q, Cui S, Ma Q, Liu Y, Yu H, Geng G, et al.
JCI Insight
. 2019 Sep;
4(18).
PMID: 31534052
Hereditary renal cystic diseases are characterized by defects in primary cilia of renal tubular epithelial cells and abnormality of tubular epithelium, which ultimately result in the development of renal cysts....
8.
Jin H, Zhang Y, Ding Q, Wang S, Rastogi P, Dai D, et al.
JCI Insight
. 2019 Jan;
4(2).
PMID: 30674725
Acute kidney injury (AKI) is a common clinical condition of growing incidence. Patients who suffer severe AKI have a higher risk of developing interstitial fibrosis, chronic kidney disease, and end-stage...
9.
Lu D, Rauhauser A, Li B, Ren C, McEnery K, Zhu J, et al.
Kidney Int
. 2016 May;
89(6):1307-23.
PMID: 27181777
Enlargement of kidney tubules is a common feature of multiple cystic kidney diseases in humans and mice. However, while some of these pathologies are characterized by cyst expansion and organ...
10.
Zhu J, Chaki M, Lu D, Ren C, Wang S, Rauhauser A, et al.
Am J Physiol Renal Physiol
. 2016 Feb;
310(9):F895-908.
PMID: 26887830
Thrombotic microangiopathy (TMA) is a disorder characterized by microvascular occlusion that can lead to thrombocytopenia, hemolytic anemia, and glomerular damage. Complement activation is the central event in most cases of...