Peter Stathopulos
Overview
Explore the profile of Peter Stathopulos including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
388
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0
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Recent Articles
1.
Ni R, Cao T, Ji X, Peng A, Zhang Z, Fan G, et al.
Cell Death Differ
. 2024 Oct;
32(2):306-319.
PMID: 39362992
DNA damage-inducible transcript 3 (DDIT3) is a well-known transcription factor that regulates the expression of apoptosis-related genes for promoting apoptosis during endoplasmic reticulum stress. Here, we report an unrecognized role...
2.
Fahrner M, Stadlbauer M, Muik M, Rathner P, Stathopulos P, Ikura M, et al.
Nat Commun
. 2018 Feb;
9(1):825.
PMID: 29483506
STIM1 and Orai1 are key components of the Ca-release activated Ca (CRAC) current. Orai1, which represents the subunit forming the CRAC channel complex, is activated by the ER resident Ca...
3.
Lian J, Cuk M, Kahlfuss S, Kozhaya L, Vaeth M, Rieux-Laucat F, et al.
J Allergy Clin Immunol
. 2017 Nov;
142(4):1297-1310.e11.
PMID: 29155098
Background: Store-operated Ca entry (SOCE) through Ca release-activated Ca channels is an essential signaling pathway in many cell types. Ca release-activated Ca channels are formed by ORAI1, ORAI2, and ORAI3...
4.
Tomar D, Dong Z, Shanmughapriya S, Koch D, Thomas T, Hoffman N, et al.
Cell Rep
. 2016 May;
15(8):1673-85.
PMID: 27184846
Mitochondrial Ca(2+) Uniporter (MCU)-dependent mitochondrial Ca(2+) uptake is the primary mechanism for increasing matrix Ca(2+) in most cell types. However, a limited understanding of the MCU complex assembly impedes the...
5.
Fahrner M, Muik M, Schindl R, Butorac C, Stathopulos P, Zheng L, et al.
J Biol Chem
. 2014 Oct;
289(48):33231-44.
PMID: 25342749
Store-operated Ca(2+) entry, essential for the adaptive immunity, is initiated by the endoplasmic reticulum (ER) Ca(2+) sensor STIM1. Ca(2+) entry occurs through the plasma membrane resident Ca(2+) channel Orai1 that...
6.
Muik M, Fahrner M, Schindl R, Stathopulos P, Frischauf I, Derler I, et al.
EMBO J
. 2011 Mar;
30(9):1678-89.
PMID: 21427704
Stromal interaction molecule (STIM1) and ORAI1 are key components of the Ca(2+) release-activated Ca(2+) (CRAC) current having an important role in T-cell activation and mast cell degranulation. CRAC channel activation...