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Peter Sperisen

Explore the profile of Peter Sperisen including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 413
Followers 0
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Recent Articles
1.
Sperisen P, Cominetti O, Martin F
Front Mol Biosci . 2015 Aug; 2:44. PMID: 26301225
Systems biology is an important approach for deciphering the complex processes in health maintenance and the etiology of metabolic diseases. Such integrative methodologies will help better understand the molecular mechanisms...
2.
Yasrebi H, Sperisen P, Praz V, Bucher P
PLoS One . 2009 Oct; 4(10):e7431. PMID: 19851466
Background: High-throughput gene expression profiling technologies generating a wealth of data, are increasingly used for characterization of tumor biopsies for clinical trials. By applying machine learning algorithms to such clinically...
3.
Krawczyk M, Seguin-Estevez Q, Leimgruber E, Sperisen P, Schmid C, Bucher P, et al.
PLoS Genet . 2008 Apr; 4(4):e1000058. PMID: 18437201
The class II trans-activator CIITA is a transcriptional co-activator required for the expression of Major Histocompatibility Complex (MHC) genes. Although the latter function is well established, the global target-gene specificity...
4.
Scheib H, Sperisen P, Hartley O
Structure . 2006 Apr; 14(4):645-7. PMID: 16615905
No abstract available.
5.
Sperisen P, Schmid C, Bucher P, Zilian O
PLoS Comput Biol . 2005 Nov; 1(6):e63. PMID: 16299590
There are a variety of bacterial defense strategies to survive in a hostile environment. Generation of extracellular polysaccharides has proved to be a simple but effective strategy against the host's...
6.
Sperisen P, Pagni M
BMC Bioinformatics . 2005 Sep; 6:216. PMID: 16135248
Background: Whole-genome sequencing projects are rapidly producing an enormous number of new sequences. Consequently almost every family of proteins now contains hundreds of members. It has thus become necessary to...
7.
Teixeira M, Arneric M, Sperisen P, Lingner J
Cell . 2004 Apr; 117(3):323-35. PMID: 15109493
Telomerase counteracts telomere erosion that stems from incomplete chromosome end replication and nucleolytic processing. A precise understanding of telomere length homeostasis has been hampered by the lack of assays that...
8.
Stauffer Y, Theiler G, Sperisen P, Lebedev Y, Jongeneel C
Cancer Immun . 2004 Feb; 4:2. PMID: 14871062
Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that became fixed in the germ line DNA millions of years ago. The fact that humoral and cellular immune responses...
9.
Sperisen P, Iseli C, Pagni M, Stevenson B, Bucher P, Jongeneel C
Nucleic Acids Res . 2003 Dec; 32(Database issue):D509-11. PMID: 14681469
We previously introduced two new protein databases (trEST and trGEN) of hypothetical protein sequences predicted from EST and HTG sequences, respectively. Here, we present the updates made on these two...