Peter R Howe
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Explore the profile of Peter R Howe including associated specialties, affiliations and a list of published articles.
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14
Citations
173
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Recent Articles
1.
Kakall Z, Kavurma M, Cohen E, Howe P, Nedoboy P, Pilowsky P
Am J Physiol Endocrinol Metab
. 2019 Apr;
317(2):E388-E398.
PMID: 31013147
The impaired ability of the autonomic nervous system to respond to hypoglycemia is termed "hypoglycemia-associated autonomic failure" (HAAF). This life-threatening phenomenon results from at least two recent episodes of hypoglycemia,...
2.
Hassanshahi M, Su Y, Khabbazi S, Fan C, Chen K, Wang J, et al.
J Cell Physiol
. 2018 Dec;
234(7):11276-11286.
PMID: 30565680
Cancer chemotherapy can cause significant damage to the bone marrow (BM) microvascular (sinusoidal) system. Investigations must now address whether and how BM sinusoidal endothelial cells (SECs) can be protected during...
3.
Fan C, Su Y, Howe P, Xian C
Int J Mol Sci
. 2018 Feb;
19(2).
PMID: 29415482
Although bone marrow and bone toxicities have been reported in breast cancer survivors, preventative strategies are yet to be developed. Clinical studies suggest consumption of long chain omega-3 polyunsaturated fatty...
4.
Su Y, Chen K, Hassanshahi M, Tang Q, Howe P, Xian C
Ann N Y Acad Sci
. 2017 Jun;
1403(1):109-117.
PMID: 28662275
Intensive cancer chemotherapy causes significant bone loss, for which the mechanisms remain unclear and effective treatments are lacking. This is a significant issue particularly for childhood cancers, as the most...
5.
Fan C, Georgiou K, Morris H, McKinnon R, Keefe D, Howe P, et al.
Breast Cancer Res Treat
. 2017 May;
165(1):41-51.
PMID: 28550626
Purpose: Anthracyclines (including doxorubicin) are still the backbone of commonly used breast cancer chemotherapy regimens. Despite increasing use of doxorubicin and cyclophosphamide (AC) combinations for treating breast cancer, their potential...
6.
Lee A, Shandala T, Soo P, Su Y, King T, Chen K, et al.
Nutrients
. 2017 Mar;
9(3).
PMID: 28282956
Intensive cancer chemotherapy is known to cause bone defects, which currently lack treatments. This study investigated the effects of polyphenol resveratrol (RES) in preventing bone defects in rats caused by...
7.
King T, Shandala T, Lee A, Foster B, Chen K, Howe P, et al.
Int J Mol Sci
. 2015 Aug;
16(8):18293-311.
PMID: 26258775
Chemotherapy-induced bone damage is a frequent side effect which causes diminished bone mineral density and fracture in childhood cancer sufferers and survivors. The intensified use of anti-metabolite methotrexate (MTX) and...
8.
Lee A, Shandala T, Nguyen L, Muhlhausler B, Chen K, Howe P, et al.
Nutrients
. 2014 Dec;
6(12):5871-87.
PMID: 25521206
Osteoporosis is a highly prevalent skeletal disorder in the elderly that causes serious bone fractures. Peak bone mass achieved at adolescence has been shown to predict bone mass and osteoporosis...
9.
Nadhanan R, Skinner J, Chung R, Su Y, Howe P, Xian C
PLoS One
. 2013 Aug;
8(8):e71592.
PMID: 23951199
Cancer chemotherapy has been shown to induce long-term skeletal side effects such as osteoporosis and fractures; however, there are no preventative treatments. This study investigated the damaging effects of anti-metabolite...
10.
Mukaro V, Costabile M, Murphy K, Hii C, Howe P, Ferrante A
Arthritis Res Ther
. 2008 May;
10(3):R57.
PMID: 18477409
Introduction: While consumption of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) has been recommended for those at risk of inflammatory disease such as rheumatoid arthritis, the mechanism of their anti-inflammatory...