Peter Olofsson
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Explore the profile of Peter Olofsson including associated specialties, affiliations and a list of published articles.
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52
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1253
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Recent Articles
1.
Olofsson P, Chipkin L, Daileda R, Azevedo R
J Math Biol
. 2023 Nov;
87(6):88.
PMID: 37994999
Asexual populations are expected to accumulate deleterious mutations through a process known as Muller's ratchet. Lynch and colleagues proposed that the ratchet eventually results in a vicious cycle of mutation...
2.
Azevedo R, Olofsson P
Math Biosci
. 2021 Sep;
341:108708.
PMID: 34560091
Evolutionary rescue is the process whereby a declining population may start growing again, thus avoiding extinction, via an increase in the frequency of fitter genotypes. These genotypes may either already...
3.
Fagevik Olsen M, Olofsson P, Frejd P, Lannefors L, Westerdahl E
Respir Care
. 2021 Feb;
66(5):862-877.
PMID: 33563794
Background: Breathing exercises with positive expiratory pressure (PEP) and oscillating PEP are common treatments for patients with respiratory impairments. There are several trials evaluating the clinical effects of a variety...
4.
Lind S, Dahlgren C, Holmdahl R, Olofsson P, Forsman H
J Leukoc Biol
. 2020 Oct;
109(6):1105-1120.
PMID: 33040403
The formyl peptide receptors FPR1 and FPR2 are abundantly expressed by neutrophils, in which they regulate proinflammatory tissue recruitment of inflammatory cells, the production of reactive oxygen species (ROS), and...
5.
Tuncel J, Holmberg J, Haag S, Hopkins M, Wester-Rosenlof L, Carlsen S, et al.
Arthritis Res Ther
. 2020 Apr;
22(1):95.
PMID: 32345366
Background: CD4 T cells play a central role during the early stages of rheumatoid arthritis (RA), but to which extent they are required for the perpetuation of the disease is...
6.
Hahn J, Euler M, Kilgus E, Kienhofer D, Stoof J, Knopf J, et al.
Redox Biol
. 2019 Jul;
26:101279.
PMID: 31349119
The phagocyte NADPH oxidase (the NOX2 complex) generates superoxide, the precursor to reactive oxygen species (ROS). ROS possess both antimicrobial and immunoregulatory function. Inactivating mutations in alleles of the NOX2...
7.
Lind S, Sundqvist M, Holmdahl R, Dahlgren C, Forsman H, Olofsson P
Biochem Pharmacol
. 2019 May;
166:163-173.
PMID: 31085160
Despite the steadily increased numbers of formyl peptide receptor (FPR) ligands identified over the years, few have been characterized in studies using animal disease models and even less have entered...
8.
Sindi S, Olofsson P
Math Popul Stud
. 2018 Oct;
20(1):1-13.
PMID: 30287982
The infectious agent of many neurodegenerative disorders is thought to be aggregates of prion protein, which are transmitted between cells. Recent work in yeast supports this hypothesis, but suggests that...
9.
Wallner F, Hultquist Hopkins M, Woodworth N, Lindvall Bark T, Olofsson P, Tilevik A
Pharmacol Res
. 2017 Oct;
128:244-251.
PMID: 29079427
Drug discovery is a constant struggle to overcome hurdles posed by the complexity of biological systems. One of these hurdles is to find and understand the molecular target and the...
10.
Sorce S, Stocker R, Seredenina T, Holmdahl R, Aguzzi A, Chio A, et al.
Free Radic Biol Med
. 2017 Aug;
112:387-396.
PMID: 28811143
Neurodegenerative disease are frequently characterized by microglia activation and/or leukocyte infiltration in the parenchyma of the central nervous system and at the molecular level by increased oxidative modifications of proteins,...